Results 81 to 90 of about 336,071 (307)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Mechanisms for Protecting Software Integrity in Networked Systems

open access: yes, 2008
Protecting software integrity is a key to successfully maintain its own credibility and reduce the financial and technical risks caused from a lack of integrity.
Kil, Chongkyung
core  

Improving the performance of power system protection using wide area monitoring systems

open access: yesJournal of Modern Power Systems and Clean Energy, 2016
Wide area monitoring (WAM) offers many opportunities to improve the performance of power system protection. This paper presents some of these opportunities and the motivation for their development. This methods include monitoring the suitability of relay
Arun G. Phadke   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Migrant Remittances and Rights to Physical Integrity: A Cross-section Study of Latin America (1981-2014)

open access: yesBrazilian Political Science Review, 2019
This article analyzes aspects of two ubiquitous phenomena in contemporary societies: migration and violations of rights to physical integrity. It focuses on violations of rights to physical integrity, such as torture and political assassination, that ...
Cristiane Lucena Carneiro, Ana Figueroa
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

T12 - Protection Systems Integrity

open access: yes, 2019
Discussion GroupAttendees Topics of Interests Reliability Limits of components and systems Considerations for new systems Interlocks Integrity Interlocks testing Surge system integrity and testing LOPA (Layer Of Protection Analysis) SIL (Safety Integrity
Kassie, Lil   +2 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

De Facto Judicial Independence and Physical Integrity Rights

open access: yes, 2013
Economists, political scientists, and legal scholars have argued that independent judiciaries have an important role to play in promoting economic development and protecting property rights.
Moyer, LP, Abouharb, MR, Schmidt, M
core  

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