Results 51 to 60 of about 7,192,626 (242)

Calculation of Optimal Vertical Protection Level Based on Integrity Risk and Continuity Risk [PDF]

open access: yesJisuanji gongcheng, 2017
In order to reduce the integrity risks and continuity risks in the process of precision vertical guidance of aircraft,and make the Receiver Autonomous Integrity Monitoring(RAIM) algorithm provide the horizontal and vertical integrity for security,this ...
YANG Kai,GUO Chengjun
doaj   +1 more source

Risk-Sensitivity in Bayesian Sensorimotor Integration

open access: yesPLoS Computational Biology, 2012
Information processing in the nervous system during sensorimotor tasks with inherent uncertainty has been shown to be consistent with Bayesian integration. Bayes optimal decision-makers are, however, risk-neutral in the sense that they weigh all possibilities based on prior expectation and sensory evidence when they choose the action with highest ...
Jordi Grau-Moya   +2 more
openaire   +6 more sources

Meta risk management and tax system integrity [PDF]

open access: yes, 2001
Meta risk management means the risk management of risk management. The Australian Taxation Office (Tax Office) has an international reputation as an organisation that is sophisticated in risk management.
Braithwaite, John   +3 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Integrity as a Control Problem: Smooth and Adaptive Protection Levels for Multi-Modal Localization

open access: yesSensors
Protection levels for autonomous vehicle localization are traditionally derived from estimator covariances under Gaussian assumptions. These approaches fail in complex urban environments where sensor anomalies produce heavy-tailed, non-Gaussian error ...
Elias Maharmeh   +2 more
doaj   +1 more source

Safeguarding integrity: a guide to the integrity system in Victoria [PDF]

open access: yes, 2014
The Safeguarding Integrity Guide aims to help public sector employees and the broader community understand Victoria\u27s integrity system and its key agencies.

core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Collision Risk Evaluation and Verification of GNSS-Based Train Integrity Detection

open access: yesApplied Sciences, 2021
To meet the demand for middle and low-density railway lines, a Global Navigation Satellite System (GNSS) based on a train integrity monitoring system (TIMS) is used for train integrity detection.
Kewei Ji   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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