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2018
Integrons are genetic recombination platforms that enhance bacterial evolvability by enabling the acquisition and differential expression of new genes. These genes are embedded in mobile elements, named cassettes, which can be stockpiled to form a long array of adaptive functions whose expression is driven by the Pc promoter within the integron ...
José Antonio Escudero +2 more
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Integrons are genetic recombination platforms that enhance bacterial evolvability by enabling the acquisition and differential expression of new genes. These genes are embedded in mobile elements, named cassettes, which can be stockpiled to form a long array of adaptive functions whose expression is driven by the Pc promoter within the integron ...
José Antonio Escudero +2 more
openaire +1 more source
Shufflons: Multiple Inversion Systems and Integrons
Annual Review of Genetics, 1999▪ Abstract Conservative site-specific recombination functions to create biological diversity in prokaryotes. Simple site-specific recombination systems consist of two recombination sites and a recombinase gene. The plasmid R64 shufflon contains seven recombination sites, which flank and separate four DNA segments.
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Class 1 integrons as invasive species
Current Opinion in Microbiology, 2017Clinical class 1 integrons are a major contributor to the evolution and dissemination of antibiotic resistance. The conserved motifs of these integrons suggest that a single, recent ancestor gave rise to all current variants. They have had a spectacular increase in distribution and abundance over the last 100 years, exhibiting many similarities to ...
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DNA as a Pollutant: the Clinical Class 1 Integron
Current Pollution Reports, 2018M. Gillings
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