Results 121 to 130 of about 313,330 (307)

Elaborating Aquinas' epistemology: From being to knowledge [PDF]

open access: yes, 2017
Amidst the broad divergence in opinion of philosophers and scientists at understanding reality that has lent character to the historical epochs of the Philosophical enterprise, the crucial realization has always been, of the necessity of Epistemology in ...
Anakwue, Nicholas
core  

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

open access: yesAdvanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura   +4 more
wiley   +1 more source

The agent intellect according to Capreolus and Cajetan [PDF]

open access: yes, 2014
En este trabajo se estudia la versión del intelecto agente según dos grandes comentadores tomistas del s. XV: Capreolo y Cayetano. El primero sostuvo que el intelecto agente es la misma alma; el segundo, que su realidad es una actividad, que es acto ...
Sellés, Juan Fernando
core  

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

open access: yesAdvanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno   +16 more
wiley   +1 more source

The new articulation of wages, rent and profit in cognitive capitalism [PDF]

open access: yes
In the transition toward a cognitive capitalism, the transformations of the social organisation of production are strictly connected to those of income distribution.
Carlo Vercellone
core  

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming

open access: yesAdvanced Materials, EarlyView.
Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung   +6 more
wiley   +1 more source

From Formal Subsumption to General Intellect: Elements for a Marxist Reading of the Thesis of Cognitive Capitalism, in Historical Materialism [PDF]

open access: yes
Since the crisis of Fordism, capitalism has been characterised by the ever more central role ofknowledge and the rise of the cognitive dimensions of labour. This is not to say that the centralityof knowledge to capitalism is new per se.
Carlo Vercellone
core  

Machine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles

open access: yesAdvanced Science, EarlyView.
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang   +7 more
wiley   +1 more source

Mystical Contemplation and Other Ways of the Cognition of God According to Saint John of the Cross

open access: yesVerbum Vitae
This philosophical article analyzes the direction of changes in human knowledge of God under the influence of mystical contemplation in the teachings of Saint John of the Cross.
Rafał Sergiusz Niziński
doaj   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

open access: yesAdvanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency   +19 more
wiley   +1 more source

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