Results 31 to 40 of about 311,384 (302)

Unconscious Thought in Peripatetic Philosophy [PDF]

open access: yes, 2014
In Aristotle’s De anima 3.5, the relation between intellect and thought, and between thought and object, is not accessible to discursive or conscious thought; an understanding of the relation requires nous, intuitive or “unconscious” thought. The “active”
Hendrix, John S
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The Agent Intellect as “form for us” and Averroes’s Critique of al-Fârâbî [PDF]

open access: yes, 2005
This article explicates Averroes\u27s understanding of human knowing and abstraction in this three commentaries on Aristotle\u27s De Anima. While Averroes\u27s views on the nature of the human material intellect changes through the three commentaries ...
Taylor, Richard C.
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Analyzing and Comparing the Ontological and Epistemological Stance of Active Intellect for Avicenna and St. Thomas [PDF]

open access: yesحکمت معاصر, 2012
The Agent intellect of Aristotle has different position in later philosophers’ thoughts. Each, according to their need and the vacuum in their philosophy would determine the position of the agent intellect.
Gholamhossein Khedri, Mastaneh Kakaii
doaj  

"Self-Knowledge and the Science of the Soul in Buridan's Quaestiones De Anima" [PDF]

open access: yes, 2017
Buridan holds that the proper subject of psychology (i.e., the science undertaken in Aristotle’s De Anima) is the soul, its powers, and characteristic functions.
Brower-Toland, Susan
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Plotinus and the Artistic Imagination [PDF]

open access: yes, 2015
In the thought of Plotinus, the imagination is responsible for the apprehension of the activity of Intellect. If creativity in the arts involves an exercise of the imagination, the image-making power that links sense perception to noetic thought and the ...
Hendrix, John S
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Mevlânâ Metafiziğinde Akıl

open access: yesTokat İlmiyat Dergisi, 2022
Bu makale, Mevlânâ’nın akıl hakkındaki görüşleriyle ilgili yanlış olduğunu düşündüğümüz yaygın bir anlayışa işaret etmeyi amaçlamaktadır. Bu yanlış anlayışa göre Mevlânâ, aklı metafizik konularda yetersiz görmektedir.
Fevzi Yiğit
doaj   +1 more source

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