Results 51 to 60 of about 37,140 (240)

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

Modulating Local Electronic Structure via Cluster Engineering on Cobalt Phosphide for Efficient Water/Seawater Splitting

Advanced Science, EarlyView.
The heterostructure benefits from the high dispersion of FeOx nanoclusters on the porous CoxP substrate, while the interfacial bonds Fe‐O‐Co enhance charge transport and redistribution, resulting in excellent oxygen evolution reaction performance and strong potential for practical applications.
Cheng Gong, Fengying Pan, Pengpeng Zhang, Yuhan Xie, Yaojie Lei, Xiaobo Zheng, Dinushi Munasinghe Mudiyanselage, Hong Gao, Jinqiang Zhang, Yufei Zhao, Guoxiu Wang, Hao Liu   +11 more
wiley   +1 more source

Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli

Advanced Science, EarlyView.
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng, Hao Liu, Haolin Han, Meng Meng, Shaojie Wang, Tianwei Tan, Haijia Su   +6 more
wiley   +1 more source

The Effect of Loan and Intellectual Capital on Profitability with Credit Risk as Moderating

Jurnal Economia, 2019
: This study aims to examine and empirically prove the moderating effects of credit risk on the relationship between the loan and intellectual capital with profitability.
Eria Latifalia Erzha, Made Sudarma, Aulia Fuad Rahman   +2 more
doaj   +1 more source

A Cascade Recognition of Activatable Probe for Fluorescence Navigation Glioblastoma Surgery: Overcoming Blood‐Brain Barrier and Off‐Target Limitations

Advanced Science, EarlyView.
A cascade recognition of activatable probe ANG‐hCy‐MC is used for high‐precision depiction of glioblastoma (GBM) margin. This probe crosses the blood‐brain barrier (BBB) through LRP1 receptor‐mediated transport and provides excellent fluorescence signal contrast between the tumor and normal tissues, thereby enabling ultra‐selective imaging and precise ...
Xinru An, Yu Guo, Yongning Bian, Yanli Tan, Chuan Fang, Hengzhu Zhang, Xueqian Chen, Lin Yuan, Dongdong Su   +8 more
wiley   +1 more source

Explaining the effective variables in measuring intellectual capital and providing the optimal model [PDF]

ارزش آفرینی در مدیریت کسب و کار
The purpose of this research is to investigate and explain the effective variables in measuring intellectual capital and to provide an optimal model. This research is developmental in terms of its purpose, analytical-correlational in terms of the type of
hatef mollazadeh jebdreghi, mahdi zeinali, ali akbar nonahal, ahmad mohamadi   +3 more
doaj   +1 more source

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

Patient‐Derived 3D‐Bioprinted Intrahepatic Cholangiocarcinoma Models Recapitulate Tumor Autologous Traits and Predict Personalized Adjuvant Therapy

Advanced Science, EarlyView.
Leveraging 3D bioprinting, this study establishes patient‐derived in vitro models of intrahepatic cholangiocarcinoma. These models faithfully recapitulate the histopathology, molecular profiles, and genomic characteristics of the original patient tumors.
Yuce Lu, Liwei Du, Minghao Sun, Kai Zhang, Mingchang Pang, Shangze Jiang, Jiaxun Dong, Xiyue Liu, Bao Jin, Fu Xu, Hang Sun, Jiangang Zhang, Huiyu Yang, Xiaobo Yang, Xin Lu, Yiyao Xu, Haitao Zhao, Shunda Du, Xinting Sang, Yongchang Zheng, Lei Zhang, Xueshuai Wan, Huayu Yang, Yilei Mao   +23 more
wiley   +1 more source

Towards a data sharing culture: recommendations for leadership from academic health centers. [PDF]

PLoS Medicine, 2008
Heather A Piwowar, Michael J Becich, Howard Bilofsky, Rebecca S Crowley, caBIG Data Sharing and Intellectual Capital Workspace   +4 more
doaj   +1 more source

Photo‐Responsive Room‐Temperature Phosphorescent Films Exhibiting Photochromism and Time‐Dependent Phosphorescent Colors for Multilevel Anti‐Counterfeiting

Advanced Science, EarlyView.
A series of photo‐responsive polymers are prepared by a facile one‐pot in situ synthesis strategy, where RTP modules and photochromic units are systematically integrated into one polymer system. The triplet‐singlet Förster resonance energy transfer (TS‐FRET) between the donor and acceptor enables the material to exhibit time‐dependent phosphorescence ...
Ziyi Bai, Xinyi Xu, Jinbo Fu, Di Zhao, Yige Wang, Huanrong Li   +5 more
wiley   +1 more source