Results 111 to 120 of about 501,307 (362)

Genetic Evidence Supporting a Role for Brain Region Volume and Functional Network Alterations in Major Depression

Advanced Science, EarlyView.
Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu, Nan Li, Yi‐Wen Lv, Wen‐Miao Yang, Zhi‐Yun Yu, Yi‐Min Zhang, Yu Guo, Xiao‐Yin Chen   +7 more
wiley   +1 more source

Developing a community-based model of care for venipuncture in children and young adults with an intellectual disability: a retrospective study

BMJ Paediatrics Open
Background Regular blood tests for monitoring metabolic side effects are often unable to be collected for people with an intellectual/developmental disability (ID/DD) and challenging behaviours (CBs) using usual pathways.
Pankaj Garg, Natasha Reid, Larissa Passarello, Catherine O’Hea, Teresa Lai, Bridget Farrell   +5 more
doaj   +1 more source

Primary care for people with an intellectual disability — what is prescribed? An analysis of medication recommendations from the BEACH dataset

BJGP Open, 2018
Background: People with intellectual disability (ID) experience a range of health disparities. Little is known about differential primary care prescribing patterns for people with and without ID.
Carmela Salomon, Helena Britt, Allan Pollack, Julian Trollor   +3 more
doaj   +1 more source

Health problems in people with intellectual disability : aspects of morbidity in residential settings and in primary health care [PDF]

, 1998
H.M.J. de Valk - van Schrojenstein Lantman
openalex   +1 more source

SGCD: High‐Resolution Spatial Domain Characterization via Data Interpolation and Cell‐Type Deconvolution

Advanced Science, EarlyView.
SGCD presents a novel approach for tissue spatial domain identification by employing interpolation to estimate inter‐spot gene expression and deconvolution to resolve cell‐type composition in both sampled and interstitial regions. By integrating gene expression, cell type, and spatial coordinates within a graph contrastive learning framework, SGCD ...
Tianjiao Zhang, Shenghe Li, Ruolan Zhang, Hongfei Zhang, Zhongqian Zhao, Hao Sun, Zhenao Wu, Guohua Wang   +7 more
wiley   +1 more source

College Student Perceptions of Varying Disability Types: Does Contact Experience Matter? [PDF]

, 2019
Studies exploring prejudices between groups have suggested that contact is related to attitudes. This relationship has been studied in the context of attitudes toward people with disabilities and has yielded inconsistent results. Other variables, such as
Anderson, Gianna
core   +1 more source

Born to Fear the Machine? Genetic and Environmental Influences on Negative Attitudes toward AI Agents

Advanced Science, EarlyView.
Why do some people fear or distrust AI agents more than others? This twin study shows that negative attitudes toward AI may partly stem from genetic factors, linking them to traits like victim sensitivity and moral beliefs. These findings show that it is not only nurture but also nature that shapes our views of AI, with implications for future human–AI
Xiaojiayu Tan, Yue He, Yuan Zhou, Xinying Li, Qingwen Ding, Yikai Tang, Yu L. L. Luo, Ruolei Gu   +7 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Health Checks for People with Down Syndrome: A Pooled Analysis of Three Randomized Controlled Trials

Disabilities
Health checks have beneficial effects on health outcomes in adults with intellectual disability; however, little is known about their effect on people with Down syndrome.
Robert S. Ware, Catherine Franklin, Lyn McPherson, Nicholas G. Lennox   +3 more
doaj   +1 more source

Health and wellbeing of people with intellectual disability in New South Wales, Australia: a data linkage cohort

BMJ Open, 2019
Purpose People with intellectual disability (ID) experience high rates of physical and mental health problems, while access to appropriate healthcare is often poor.
Kimberlie Dean, Simone Reppermund, Theresa Heintze, Preeyaporn Srasuebkul, Rebecca Reeve, Melinda Smith, Eric Emerson, Phillip Snoyman, Eileen Baldry, Leanne Dowse, Tracey Szanto, Grant Sara, Tony Florio, Anina Johnson, Melissa Clements, Kathryn McKenzie, Julian Trollor   +16 more
doaj   +1 more source