Results 111 to 120 of about 1,423,846 (344)

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Effectiveness of the Beat the Kick intervention in addressing substance abuse among adults with mild intellectual disabilities in the Netherlands: study protocol for an open-label, multicenter, superiority randomized controlled trial

Trials
Background People with mild intellectual disabilities (MID) are at elevated risk of substance-use problems. Beat the Kick is a motivation-focused, MID-adapted pre-treatment program.
Rosemarie Gideonse, Noud Frielink, Carlo Schuengel, Joanneke E.L. van der Nagel, Petri J.C.M. Embregts   +4 more
doaj   +1 more source

Cancer screening participation and outcomes among people with an intellectual disability in the Netherlands: a cross-sectional population-based study

The Lancet Public Health
Summary: Background: People with an intellectual disability face diverse health disparities, including challenges accessing cancer care. In the Netherlands, as in many other countries, there are national screening programmes for early detection of ...
Amina Banda, MSc, Maarten Cuypers, PhD, Jenneken Naaldenberg, PhD, Aura Timen, ProfMD, Geraline Leusink, ProfMD   +4 more
doaj   +1 more source

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

Quality of life of families with children with intellectual and developmental disabilities: Family health domain

, 2023
Anka Vukičević, Emira Švraka, Amra Mačak Hadžiomerović, Naim Salkić   +3 more
openalex   +2 more sources

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

Advanced Science, EarlyView.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song, Yu Wei, Peng Jia, Shan He, Qian Wang, Manman Xu, Hongzhi Liu, Pengtao Bao, Shanyue Guan, Xiaozhong Qu   +9 more
wiley   +1 more source

Developing a community-based model of care for venipuncture in children and young adults with an intellectual disability: a retrospective study

BMJ Paediatrics Open
Background Regular blood tests for monitoring metabolic side effects are often unable to be collected for people with an intellectual/developmental disability (ID/DD) and challenging behaviours (CBs) using usual pathways.
Pankaj Garg, Natasha Reid, Larissa Passarello, Catherine O’Hea, Teresa Lai, Bridget Farrell   +5 more
doaj   +1 more source

Physical fitness of individuals with intellectual disability who have Special Olympics experience [PDF]

, 2016
Pauli Rintala, Piritta Asunta, Jukka Lahti, E. Michael Loovis   +3 more
openalex   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Health Checks for People with Down Syndrome: A Pooled Analysis of Three Randomized Controlled Trials

Disabilities
Health checks have beneficial effects on health outcomes in adults with intellectual disability; however, little is known about their effect on people with Down syndrome.
Robert S. Ware, Catherine Franklin, Lyn McPherson, Nicholas G. Lennox   +3 more
doaj   +1 more source