Results 111 to 120 of about 475,058 (385)

Unraveling Neurodevelopment: Synergistic Effects of Intrinsic Genetic Programs and Extrinsic Environmental Cues

open access: yesAdvanced Science, EarlyView.
Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang   +4 more
wiley   +1 more source

Psychotropic medicines’ prevalence, patterns and effects on cognitive and physical function in older adults with intellectual disability in Ireland: longitudinal cohort study, 2009–2020

open access: yesBJPsych Open
Background The frequent prescribing of psychotropics and high prevalence of polypharmacy among older adults with intellectual disabilities require close monitoring.
Marina Odalović   +13 more
doaj   +1 more source

Emerging Topics in Assistive Reading Technology: From Presentation to Content Accessibility [PDF]

open access: yesarXiv, 2017
With the recent focus in the accessibility field, researchers from academia and industry have been very active in developing innovative techniques and tools for assistive technology. Especially with handheld devices getting ever powerful and being able to recognize the user's voice, screen magnification for individuals with low-vision, and eye tracking
arxiv  

Expanding Access to Music Technology -- Rapid Prototyping Accessible Instrument Solutions For Musicians With Intellectual Disabilities [PDF]

open access: yesarXiv, 2020
Using open-source and creative coding frameworks, a teamof artist-engineers from Portland Community College work-ing with artists who experience Intellectual/Developmentaldisabilities prototyped an ensemble of adapted instrumentsand synthesizers that facilitate real-time in-key collabora-tion.
arxiv  

Recommendations For Speakers in Meetings and Conferences [PDF]

open access: yes, 2007
[Excerpt] It is not easy for a speaker to prepare documents and presentations especially when speaking to diverse audiences, i.e. when people have different languages, different backgrounds, different level of knowledge or include people with ...
The European Association of Societies of Persons with Intellectual Disabilities
core   +1 more source

RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development

open access: yesAdvanced Science, EarlyView.
The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao   +9 more
wiley   +1 more source

Intellectual disability content within tertiary medical curriculum: how is it taught and by whom?

open access: yesBMC Medical Education, 2018
Background Individuals with intellectual disability experience higher rates of physical and mental health conditions compared with the general population, yet have inequitable access to health care services.
Julian N. Trollor   +8 more
doaj   +1 more source

Traumatic experiences and life events in people with \ud intellectual disability [PDF]

open access: yes, 2008
Purpose of review \ud The aim of this article is to present and critically evaluate recent research on life events and traumatic experiences as predictors of psychopathology in people with intellectual \ud disability. \ud \ud Recent findings \ud The area
Martorell, Almudena, Tsakanikos, Elias
core  

Mental health problems in children with intellectual disability [PDF]

open access: yes, 2022
Intellectual disability ranks in the top ten causes of disease burden globally and is the top cause in children younger than 5 years. 2-3% of children have an intellectual disability, and about 15% of children present with differences consistent with an ...
Absoud, Michael   +4 more
core  

The Dynamic Landscape of 3′‐UTR Alternative Polyadenylation Across Mouse Fetal Development and Anatomy

open access: yesAdvanced Science, EarlyView.
This work maps 3′‐UTR APA across mouse fetal development and tissues, identifying conserved sequence determinants that influence pAS choice. In fetal brain tissues, complex APA dynamics during development are potentially regulated by RBPs like Rbm38, which restrict distal pAS usage.
Qin Wang, Xin Chen, Xiao‐Ou Zhang
wiley   +1 more source

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