Results 51 to 60 of about 1,704,824 (318)

Editorial on Psychological distress in the Greek general population during the first COVID-19 lockdown

BJPsych Open, 2021
This editorial discusses a study by Karaivazoglou and colleagues, where the authors investigated anxiety, depressive, post-traumatic stress-related symptoms and coronavirus disease 2019 (COVID-19)-related beliefs in the Greek population during the first ...
Samuel Tromans
doaj   +1 more source

Awareness of the Need for Change: A Constructivist Grounded Theory of Medical Students’ Understanding of Human Rights in Mental Health [PDF]

Health and Human Rights, 2023
Traditionally, teaching in psychiatry has had a passing focus on human rights. Against this backdrop, the aim of this study was to construct a theory of the learning value of a service user-led human rights-focused teaching program for final-year medical
Peter Macsorley, Sarah Gordon, Tracey Gardiner, Giles Newton-Howes   +3 more
doaj  

Movement side effects of antipsychotic drugs in adults with and without intellectual disability: UK population-based cohort study [PDF]

, 2017
OBJECTIVES: To measure the incidence of movement side effects of antipsychotic drugs in adults with intellectual disability and compare rates with adults without intellectual disability. DESIGN: Cohort study using data from The Health Improvement Network.
Hassiotis, A, Horsfall, L, Osborn, D, Sheehan, R, Strydom, A, Walters, K   +5 more
core   +2 more sources

Neuronal mechanisms of mutations in SCN8A causing epilepsy or intellectual disability

Brain : a journal of neurology, 2019
Ion channel mutations can cause distinct neuropsychiatric diseases. We first studied the biophysical and neurophysiological consequences of four mutations in the human Na+ channel gene SCN8A causing either mild (E1483K) or severe epilepsy (R1872W), or ...
Yuanyuan Liu, J. Schubert, L. Sonnenberg, K. Helbig, C. Hoei-Hansen, M. Koko, Maert Rannap, S. Lauxmann, Mahbubul Huq, Michael C. Schneider, K. Johannesen, G. Kurlemann, E. Gardella, F. Becker, Y. Weber, J. Benda, R. Møller, H. Lerche   +17 more
semanticscholar   +1 more source

Comorbid Intellectual Disability [PDF]

Deutsches Ärzteblatt international, 2014
The article by Lehnhardt and colleagues successfully links empirically based facts with the authors' own clinical experiences from a specialized outpatient clinic for people with high-functioning autism; it can therefore be used as a practice guideline for the diagnostic evaluation of adults with suspicion of autism spectrum disorders (1).
Tanja Sappok, Albert Diefenbacher, Thomas Bergmann   +2 more
openaire   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao, Katherine R Schon, Jana Vandrovcova, Özlem Yayıcı Köken, Sharika Raga, Kireshnee Naidu, Maryke Schoonen, Nimita Rani, Pedro Tomaselli, Dipti Baskar, Musambo Kapapa, Ipek Polat, Lindsay A Wilson, Kumarasamy Thangaraj, Uluç Yiş, Bevinahalli N Nandeesh, David Bearden, Michelle Kvalsund, Franclo Henning, Seena Vengalil, Atchayaram Nalini, Claudia F. R. Sobreira, Wilson Marques, Haluk Topoloğlu, Michael G Hanna, Sireesha Yareeda, Venugopalan Y Vishnu, Francois H van der Westhuizen, Izelle Smuts, Surita Meldau, Jo Wilmshurst, Büşranur Çavdarlı, Jeannine Heckmann, Patrick F Chinnery, Rita Horvath   +34 more
wiley   +1 more source

Spinal Cord Abnormalities in Early Pediatric Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Spinal cord lesions and atrophy in the cervical region are common in adult multiple sclerosis (MS) and correlate with disability. Whether similar abnormalities occur in pediatric MS patients is largely unknown. Clinical and MRI evaluations were performed in 38 pediatric MS patients and 13 healthy controls (HC).
Monica Margoni, Paola Valsasina, Paolo Preziosa, Martina Rubin, Mor Gueye, Lucia Moiola, Maria Assunta Rocca, Massimo Filippi   +7 more
wiley   +1 more source

The effectiveness of a weight maintenance intervention for adults with intellectual disabilities and obesity: a single stranded study [PDF]

, 2015
Background: The evidence base for weight management programmes incorporating a weight loss and a weight maintenance phase for adults with intellectual disabilities (ID) is limited.
Hankey, Catherine, Melville, Craig, Spanos, Dimitrios   +2 more
core   +1 more source

Early 17β-estradiol treatment reduces seizures but not abnormal behaviour in mice with expanded polyalanine tracts in the Aristaless related homeobox gene (ARX)

Neurobiology of Disease, 2021
Children with severe intellectual disability have an increased prevalence of refractory seizures. Steroid treatment may improve seizure outcomes, but the mechanism remains unknown.
Karagh E. Loring, Tessa Mattiske, Kristie Lee, Aneta Zysk, Matilda R. Jackson, Jeffrey L. Noebels, Cheryl Shoubridge   +6 more
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