Results 81 to 90 of about 185,257 (294)

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Effects of face coverings on people and interactions in mental health settings: scoping review

BJPsych Open
Background Early in the SARS–CoV-2 pandemic, most jurisdictions implemented mandatory face covering policies across healthcare settings. This intervention, which lasted multiple years, was unprecedented in psychiatry.
Paul Van Houtte, Félix Lamarche, Susanna Every-Palmer   +2 more
doaj   +1 more source

MCDONAGH, Patrick; GOODEY, C.F.; STAINTON, Tim (eds.) (2021). Intellectual disability. A conceptual history, 1200-1900. Manchester University Press, 272 pp., ISBN 978-1-5261-5164-3

, 2022
João Nunes
openalex   +2 more sources

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

Advanced Science, EarlyView.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng, Ge Zhu, Siyu Sun, Wenbo Yao, Yuning Zhang, Yong‐Guang Yang, Tianmeng Sun   +6 more
wiley   +1 more source

ChatCFD: A Large Language Model‐Driven Agent for End‐to‐End Computational Fluid Dynamics Automation with Structured Knowledge and Reasoning

Advanced Intelligent Discovery, EarlyView.
Chat computational fluid dynamics (CFD) introduces an large language model (LLM)‐driven agent that automates OpenFOAM simulations end‐to‐end, attaining 82.1% execution success and 68.12% physical fidelity across 315 benchmarks—far surpassing prior systems.
E Fan, Kang Hu, Zhuowen Wu, Jiangyang Ge, Jiawei Miao, Yuzhi Zhang, He Sun, Weizong Wang, Tianhan Zhang   +8 more
wiley   +1 more source

A Multimodal Intelligent System for Human Digital Twin Simulation with Continuous Kinematic Data Tracking, Biometric Prognosis, and Cognitive State Feedback in Industrial Environments

Advanced Intelligent Discovery, EarlyView.
This article implements a unified human digital twin framework that integrates cutting edge actuation, sensing, simulation, and bidirectional feedback capability. The approach includes integrating multimodal sensing, AI, and biomechanical simulation into one compact system.
Tajbeed Ahmed Chowdhury, Sebastian Gratz‐Kelly, Eric Wagner, Paul Motzki, Martina Lehser   +4 more
wiley   +1 more source

Effectiveness of the Beat the Kick intervention in addressing substance abuse among adults with mild intellectual disabilities in the Netherlands: study protocol for an open-label, multicenter, superiority randomized controlled trial

Trials
Background People with mild intellectual disabilities (MID) are at elevated risk of substance-use problems. Beat the Kick is a motivation-focused, MID-adapted pre-treatment program.
Rosemarie Gideonse, Noud Frielink, Carlo Schuengel, Joanneke E.L. van der Nagel, Petri J.C.M. Embregts   +4 more
doaj   +1 more source

Injectable contraceptive use in women with intellectual disability: narrative review and service evaluation

BJPsych Open
Background Intellectual disability is defined as an IQ of 70 or below. Women with intellectual disability frequently experience menstrual distress leading to the use of hormonal medications such as depot medroxyprogesterone acetate (DMPA).
Marianne Bergman, Alaa Martin
doaj   +1 more source

Participation for mental health service development in China: Conditions, challenges, facilitators, and outcomes

American Journal of Community Psychology, EarlyView.
Abstract This study analyzes a participatory project to develop peer support services for people with serious mental illnesses (SMIs) in China. Drawing on interviews with psychiatrists, social workers, service users, and a family caregiver, it examines the conditions, challenges, facilitators, and outcomes of participation in a paternalistic context ...
Zhiying Ma, Yu Fan, Xiyuan Chen, Lindsay Sheehan, Sang Qin, Aoxuan Cao, Liang Zhou   +6 more
wiley   +1 more source

Work Disability, Early Retirement, and Loss of a Loved One in the World Trade Center Health Registry Cohort

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Existing research on the economic outcomes of 9/11 remains limited and has primarily focused on early retirement. Little is known about the prevalence of work disability and loss of a loved one and whether they are associated with survey attrition.
Jennifer Brite, Matthew Di Vitto, Janna Metzler   +2 more
wiley   +1 more source