Results 81 to 90 of about 2,601,816 (350)

Measurement invariance in the assessment of people with an intellectual disability [PDF]

, 2011
Intellectual assessment is central to the process of diagnosing an intellectual disability and the assessment process needs to be valid and reliable. One fundamental aspect of validity is that of measurement invariance, i.e.
MacLean, Hannah, Kidd, Gill, Schwannauer, Matthias, Aja L. Murray, Gill Kidd, Hannah MacLean, Karen McKenzie, Matthias Schwannauer, Murray, Aja Louise, McKenzie, Karen   +9 more
core   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

Planning services for people with disabilities: a guide to the Intellectual Disability Database.

, 2001
To monitor current service provision To predict future service requirements for research A summary of the current level of service provision is provided each year in the Annual Report of the National Intellectual Disability Database Committee.
National Intellectual Disability Database Committee, Department of Health and Children, National Association of the Mentally Handicapped in Ireland   +2 more
core  

Maternal Hyperglycemia Disrupts Cerebral Cortex Development Through the Foxp1‐Dll1‐Notch Axis

Advanced Science, EarlyView.
Maternal hyperglycemia disrupts offspring cortical development through a Foxp1–Dll1–Notch signaling axis. In a PGDM mouse model, intrauterine hyperglycemia decreases cortical thickness and perturbs neuronal layering by downregulating Foxp1, which transcriptionally regulates the Notch ligand Dll1.
Longkai He, Ya Jin, Guosheng Liu, Hao Liu, Xinyi Zhu, Weipeng Xu, Wei Li, Meiyao He, Yao Shen, Bingxiao Li, Xuesong Yang, Xiaoyu Wang, Shasha Han   +12 more
wiley   +1 more source

Identification of SETBP1 Mutations by Gene Panel Sequencing in Individuals With Intellectual Disability or With “Developmental and Epileptic Encephalopathy”

Frontiers in Neurology, 2020
SETBP1 mutations are associated with the Schinzel-Giedion syndrome (SGS), characterized by profound neurodevelopmental delay, typical facial features, and multiple congenital malformations (OMIM 269150).
Emanuela Leonardi, Emanuela Leonardi, Elisa Bettella, Elisa Bettella, Maria Federica Pelizza, Maria Cristina Aspromonte, Maria Cristina Aspromonte, Roberta Polli, Roberta Polli, Clementina Boniver, Stefano Sartori, Donatella Milani, Alessandra Murgia, Alessandra Murgia   +13 more
doaj   +1 more source

Other title: Client Assessment Referral and Evaluation Level II Instruction Manual : Intellectual/Developmental Disability Other title: Level II Instruction Manual : Intellectual/Developmental Disability Other title: Intellectual/Developmental Disability

, 2015
"Effective July 1, 2015.""Instructions for CARE Level II Preadmission Screening for Intellectual/Developmental Disability and Other Related ...
Kansas. Department for Aging and Disability Services. CARE Program.
core  

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

Advanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li, Xuanyue Ma, Zhenyu Ding, Bang Sun, Linglin Liu, Hei Matthew Yip, Wei Wang, Tianying Wu, Yuan Guo, Yinghui Peng, Shiqing Zhang, Jacque Pak Kan Ip, Li Zhang, Keshen Li, Lei Shi   +14 more
wiley   +1 more source

Late-onset diagnosis of SHINE syndrome in an adolescent with developmental delay: Case report

SAGE Open Medical Case Reports
Sleep disturbances, hypotonia, intellectual disability, neurological disorders, and epilepsy (SHINE) syndrome is a rare autosomal dominant neurodevelopmental disorder. A mutation in the DLG-4 gene on chromosome 17 causes SHINE syndrome.
Mohamed Zebda, Isaiah Carter, Sierra Cowan   +2 more
doaj   +1 more source

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

Advanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau, John J. Foxe, Shlomit Beker, Sophie Molholm   +3 more
wiley   +1 more source

Classification and intellectual disabilities: an investigation of the factors that predict the performance of athletes with intellectual disability [PDF]

, 2018
It has been shown that having intellectual disabilities impacts to reduce performance compared to athletes without this impairment. However, it has also been demonstrated that there is a not a direct link between intelligence and athletic performance. To
Jan Burns, Gilderthorp, R., Rosanna Gilderthorp, Jones, F., Fergal Jones, Burns, J.   +5 more
core   +1 more source