Results 141 to 150 of about 172,093 (307)

Nano‐Gs Protein Peptidomimetics: Rational Design of Gα C‐Terminus‐Derived Peptides Mimicking Key Components of Gs‐β2AR Interactions

open access: yesAngewandte Chemie International Edition, EarlyView.
G protein‐coupled receptors (GPCRs) are major therapeutic targets. Modulating GPCR activity through intracellular sites is evolving. A structure‐ and computation‐assisted approach generated small G protein‐derived peptidomimetics targeting the intracellular binding crevice of the β2 adrenergic receptor mimicking features of the full G protein.
Phuong Thu Tran   +11 more
wiley   +1 more source

Follow the Intellectual Property, How does Industry pay Programmers' Salaries when they move the related IP rights to offshore taxhavens?" [PDF]

open access: yes
In the ongoing discussion about offshoring in the computer and data-processing industries, the 2006 ACM report Globalization and Offshoring of Software addressed job shifts due to globalization in the software industry.
Wiederhold, Gio
core   +1 more source

A dancing bear, a colleague, or a sharpened toolbox? The cautious adoption of generative artificial intelligence technologies in digital humanities research

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract The emergence of generative artificial intelligence (GenAI) is reshaping the research landscape and carries significant implications for Digital Humanities (DH), a field long intertwined with computational methods and technologies. This study examines how DH scholars are adopting and critically evaluating GenAI in their research. Drawing on an
Rongqian Ma, Meredith Dedema, Andrew Cox
wiley   +1 more source

IP dLedger - Decentralized ledger for intellectual property administration

open access: yesTechnological Forecasting and Social Change, 2023
Ji-Hyun Nam   +3 more
openaire   +1 more source

Developing a critical caste analysis within information science and technology: A research review: An annual review of information science and technology paper

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract Caste—an ascriptive social hierarchy in South Asia and its diaspora—is a globalized phenomenon. Recent caste‐based discrimination, particularly in technology companies and anti‐caste efforts to address it, has compelled academia, policy, and the technology industry to better understand contemporary mechanics of caste.
Nayana Kirasur, Britt Paris
wiley   +1 more source

What is Your Software Worth? [PDF]

open access: yes
This article presents a method for valuing software based on the income that use of that software is expected to generate in the future. Well-known principles of intellectual property (IP) valuation, sales expectations, discounting to present value, and ...
Wiederhold, gio
core   +1 more source

Labor Epidural Analgesia and Autism Spectrum Disorder in Offspring: A Population‐Based Case–Control Study

open access: yesAutism Research, EarlyView.
ABSTRACT While the immediate benefits of labor epidural analgesia (LEA) are well established, recent studies have raised concerns about possible associations with autism spectrum disorder (ASD). Therefore, we examined the association between LEA and ASD in offspring.
Taniqua T. Ingol   +7 more
wiley   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie   +17 more
wiley   +1 more source

IP Law and Antitrust Law Complementarity when Property Rights are Incomplete [PDF]

open access: yes
This paper explores the interface between two important institutional pillars of market exchange – Intellectual Property (IP) law and Antitrust law – in light of a theory of property rights incompleteness. This theory interprets property as an incomplete
Antonio Nicita   +2 more
core  

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