Results 231 to 240 of about 10,364,935 (290)

Integrating Somatic and Germline Pharmacogenomics for Therapeutic Decisions in Precision Oncology. [PDF]

open access: yesJCO Precis Oncol
Pathak VS   +6 more
europepmc   +1 more source

Graphene Aerogels With Spherical Pore Structure for Broad Frequency Regulation and Enhanced Low‐Frequency Response

open access: yesAdvanced Science, EarlyView.
A graphene aerogel with a spherical‐pore structure is constructed via microbubble templating. This unique architecture suppresses strain‐induced percolation of conductive networks, enabling dynamic frequency tuning. It also delivers enhanced low‐frequency absorption with an effective absorption bandwidth of 2.56 GHz, covering 91% of the low‐frequency ...
Liang Li   +7 more
wiley   +1 more source

PRMT5‐Dependent Stabilization of VPS34 Orchestrates Copper Trafficking to Shield Cancer Cells from Cuproptosis and Radiotherapy

open access: yesAdvanced Science, EarlyView.
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen   +17 more
wiley   +1 more source

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao   +11 more
wiley   +1 more source

Development and Validation of a Computational Histology Artificial Intelligence-Powered Biomarker in Metastatic Hormone-Sensitive Prostate Cancer on Randomized Phase III Trials. [PDF]

open access: yesJCO Precis Oncol
Sweeney CJ   +27 more
europepmc   +1 more source

First abundance estimate for greater Caribbean manatees (Trichechus Manatus Manatus) in Belize. [PDF]

open access: yesSci Rep
Edwards HH   +7 more
europepmc   +1 more source

Chung-Jansen Syndrome in a Young Woman with a PHIP Variant: Severe Obesity, Intellectual Disability, and Endocrine Abnormalities. [PDF]

open access: yesJ Clin Med
Donno F   +9 more
europepmc   +1 more source

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