Results 51 to 60 of about 322,271 (302)

The Future of the Journal? Integrating research data with scientific discourse [PDF]

, 2010
To advance the pace of scientific discovery we propose a conceptual format that forms the basis of a truly new way of publishing science. In our proposal, all scientific communication objects (including experimental workflows, direct results, email ...
Anita de Waard
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

LOCAL MARKETS OF INTANGIBLE ASSETS IN THE CONTEXT OF THE TRANSFORMATION OF THE REGIONAL ECONOMY

Вестник Северо-Кавказского федерального университета, 2022
The article is devoted to the most pressing issues of research into the role of intangible assets in the sustainable development of the regional economy.
O. Opyatova
doaj   +1 more source

Methodology of Intellectual Property Objects Commercial Potential Evaluation

IOP Conference Series: Materials Science and Engineering, 2020
Abstract The current state of the world economy and crisis phenomena show that the sustainable development of national economies is possible with the development of science and technology embodied in technologies, equipment and personnel qualification systems, production organization.
Boris Lyamin, Vladimir Ulanov, Tatiana Cherkasova, Olga Milkova   +3 more
openaire   +1 more source

Upper Bound on the Products of Particle Interactions in Cellular Automata [PDF]

, 2001
Particle-like objects are observed to propagate and interact in many spatially extended dynamical systems. For one of the simplest classes of such systems, one-dimensional cellular automata, we establish a rigorous upper bound on the number of distinct ...
Ablowitz, Boccara, Boccara, Boccara, Cosma Rohilla Shalizi, Cross, Crutchfield, Crutchfield, Crutchfield, Crutchfield, Eloranta, Eloranta, Eloranta, Goldberg, Grassberger, Griffeath, Hanson, Hanson, Jakubowski, James P Crutchfield, Lindgren, Moore, Park, Peyrard, Steiglitz, Wim Hordijk, Wuensche, Yunes   +27 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Non-contractual obligations in intellectual property law

Хабаршы. Заң сериясы, 2022
The article deals with obligations as the basis for the emergence of civil law relations, in connection with this, the specificity of non-contractual obligations is revealed.
A. Аmangeldy
doaj   +1 more source

Мотивування працівників до створення обʼєктів інтелектуальної власності [PDF]

, 2016
У статті обґрунтовано важливість дослідження особливостей мотивування працівників до створення об’єктів інтелектуальної власності. Встановлено, що в економічно розвинених країнах стимулюванню інтелектуальної діяльності працівників надається першорядне ...
Іваницька, С. Б.
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Post-it note [PDF]

, 2019
The chapter offers the intellectual property law history (mostly patents and trade marks) of one of the most popular and innovative everyday objects, the “post-it”.
Karapapa, Stavroula
core   +1 more source