Results 61 to 70 of about 8,678 (262)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Developing intellectual property management system in healthcare

Вестник университета
The modern system of state regulation to a large extent provides legal protection of intellectual property objects, which is an important step in creating an innovative environment for organizations.
V. S. Eminova
doaj   +1 more source

Problems of Recognition of Scientific Discovery as Object of Intellectual Property [PDF]

Societas et Iurisprudentia, 2018
The paper analyses the problems which prevent the recognition of the scientific discoveries as the legitimate objects of intellectual property. The subjects of the research are the definition and characteristics of the scientific discovery in the ...
Andrey Alekseyevich Bogustov
doaj  

Statistics and Characteristics Analysis of China’s Intellectual Property Crimes

MATEC Web of Conferences, 2018
By collecting, comparing and analyzing the data of intellectual property crime cases officially published, it is found that there is a big contrast between the quantity and the actual situation.
Bao Yingyu
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

PROBLEMATIC ASPECTS OF DIGITALIZATION OF THE INTELLECTUAL PROPERTY MARKET IN THE CONTEXT OF UKRAINE'S INTEGRATION PROCESSES WITH THE EU

Публічне управління та регіональний розвиток
The article analyzes the peculiarities of the intellectual property market in Ukraine. The author identifies, summarizes and provides a brief description of the types and subjects of market relations in the field of intellectual property.
Dmytro Slobodianiuk
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Objects of intellectual property of military personnel

Uzhhorod National University Herald. Series: Law
The article is devoted to the study of legal mechanisms for regulating objects of intellectual property (hereinafter - OIP) created by military personnel during the performance of their official duties. In the context of modern challenges associated with the military aggression of the Russian Federation and the processes of European integration of ...
openaire   +3 more sources

INDUSTRIAL DESIGN AND MUSEUM OBJECTS: RESULTS OF THEIR COMPARATIVE LEGAL ANALYSIS AS OBJECTS OF INTELLECTUAL PROPERTY

Russian Studies in Law and Politics
The subject of the presented paper is the normative foundations and doctrinal approaches to industrial designs and museum objects as intellectual property objects, which is predetermined by the purpose of the research, which is to identify the ...
Gennady B. Zolotov
doaj   +1 more source

Intellectual property management for SMEs

International Journal of Financial Studies, Economics and Management, 2023
As a fundamental element of the knowledge economy, intellectual property is widely used in the modern management of companies. Awareness of the fact that, as a carrier of knowledge intellectual property can become a competitive advantage, requires ...
Ventsislava Nikolova-Minkova
doaj