Results 121 to 130 of about 181,862 (308)
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Advanced Science, EarlyView.Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Review of Vrinda Dalmiya's 'Caring to Know' [PDF]
, 2018 'Caring to Know' argues that “caring is not the ‘other’ of reason and that our lived experiences of caring and being cared for can be useful resources for truth-seeking” (1).
Kirloskar-Steinbach, Monika
core
Advanced Science, EarlyView.Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang +9 more
wiley +1 more source
Integrative Approaches to Treating Cellular Senescence in Kidney Disease
Advanced Science, EarlyView.ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa +3 more
wiley +1 more source
Advanced Science, EarlyView.By engineering the PVA/H3PO4 ionic elastomer with optimized viscoelasticity and a height‐graded microstructure, the pressure sensor achieves a broad linear range up to 2000 kPa and a high sensitivity of 2.70 nF/kPa. These advancements underscore its strong potential for wearable electronics, including bio‐signal detection, health monitoring, and ...
Allen J. Cheng +13 more
wiley +1 more source
The Role of Virtues in Legal Education
Oñati Socio-Legal Series, 2016 The author applies virtue theory (virtue epistemology and virtue ethics in particular) to the question of legal education and examines the prospects of a virtue-based discourse in this context.
Antal Szerletics
doaj
The Virtues of Redundancy in Legal Thought [PDF]
, 1990 Redundancy has a bad reputation among legal intellectuals. When someone says, for example, that the ninth and tenth amendments are redundant, we can be pretty sure that this person attaches little importance to these constitutional provisions.
Barnett, Randy E
core +2 more sources
Advanced Science, EarlyView.Three CDs‐Fe nanozymes functionalized with tailor‐made ligands (TPP, HEDP, and DTPA) are synthesized via hydrothermal carbonization and coordination chemistry. A ligand‐regulation strategy for CDs‐Fe nanozymes achieves tunable enzyme‐mimicking activities and a powerful synergistic effect between POD and UV‐induced OXD pathways, paving the way for ...
Xiangli Li +4 more
wiley +1 more source
Advanced Science, EarlyView.High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani +10 more
wiley +1 more source
Advanced Science, EarlyView.The redox‐active nature of NiOx enables ultrafast oxidative doping of spiro‐OMeTAD within seconds. Concurrently, NiOx‐Li+ coordination complexes formed during this redox process are selectively removed by filtration, effectively extracting residual Li+ ions from the film.
Yun Seop Shin +19 more
wiley +1 more source