Results 141 to 150 of about 942,007 (409)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Journal of CO2 UtilizationThe use of CO2/H2 for amine N-methylation provides a green and sustainable pathway for CO2 utilization and the production of N-methylamines. However, the research on advanced catalysts still poses a challenge.
Jianfang Liu +5 more
doaj +1 more source
, 2013 This policy letter sheds light on the economic and political backround in Cyprus and provides an analyses of the factors which lead to an intensification of the crisis there.
Orphanides, Athanasios
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Intensified therapy for infants with acute lymphoblastic leukemia [PDF]
, 1997 Lewis B. Silverman +6 more
openalex +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Angular accelerometer Patent [PDF]
, 1967 Strain gage accelerometer for angular acceleration ...
Richard, R. R.
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
A Malthusian model for all seasons? [PDF]
An issue often discussed in relation to agricultural development is the effect on agricultural labour productivity of more intensive land-use. Introducing aspects of seasonality into a stylized Malthusian model, we unify two diverging views by showing ...
Jacob L. Weisdorf, Paul Sharp
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