Results 151 to 160 of about 131,298 (249)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

How does agricultural intensification impact insect diversity and abundance in the palm groves of Algeria's Sahara? [PDF]

Biodivers Data J
Boukhelouf W, Benzina I, Si Bachir A, Marniche F.   +3 more
europepmc   +1 more source

System of wheat intensification (SWI) – A new approach for increasing wheat yield in small holder farming system

, 2017
Lalita Rana, Hirak Banerjee, Krishnendu Ray, Sukamal Sarkar   +3 more
openalex   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Incidence of treatment intensification based on HbA1c trends in people with type 2 diabetes. [PDF]

J Diabetes Investig
Sugito E, Sugiyama T, Bouchi R, Tanabe A, Ueki K, Ohsugi M.   +5 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

When Clearing Out an Old House Advances Science: The Hump-Shaped Diversity Distribution in Central European Grasslands Better Explained. [PDF]

Glob Chang Biol
Vittoz P.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Spot Farming for sustainable intensification of plant production.

, 2018
Juliana Wegner, Dieter von Hörsten, Lisa-Marie Urso   +2 more
openalex   +1 more source

Soil carbon stock and humification in pastures under different levels of intensification in Brazil

, 2018
A. Segnini, Alfredo Augusto Pereira Xavier, Pedro Luís Otaviani-Junior, P. P. A. Oliveira, A. de F. Pedroso, Maria Fernanda Ferreira Menegucci Praes, Paulo Henrique Mazza Rodrigues, D. M. B. P. Milori   +7 more
openalex   +1 more source