Results 121 to 130 of about 154,558 (375)

Comparison of simple and complex liver intensity modulated radiotherapy

Radiation Oncology, 2010
Background Intensity-modulated radiotherapy (IMRT) may allow improvement in plan quality for treatment of liver cancer, however increasing radiation modulation complexity can lead to increased uncertainties and requirements for quality assurance.
Eccles Cynthia L, Purdie Thomas G, Lee Mark T, Sharpe Michael B, Dawson Laura A   +4 more
doaj   +1 more source

Dosimetric Comparison and Evaluation of 4 Stereotactic Body Radiotherapy Techniques for the Treatment of Prostate Cancer [PDF]

, 2016
Purpose:The aim of this study was to compare dosimetric characteristics, monitor unit, and delivery efficiency of 4 different stereotactic body radiotherapy techniques for the treatment of prostate cancer.Methods:This study included 8 patients with ...
Kaleva, Erna, Keyrilainen, Jani, Sailas, Liisa, Seppala, Jan, Suilamo, Sami, Tenhunen, Mikko, Virsunen, Heli   +6 more
core   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Forward-planned intensity modulated radiation therapy using a cobalt source: A dosimetric study in breast cancer

Journal of Medical Physics, 2013
This analysis evaluates the feasibility and dosimetric results of a simplified intensity-modulated radiotherapy (IMRT) treatment using a cobalt-therapy unit for post-operative breast cancer. Fourteen patients were included.
Savino Cilla, Joseph Kigula-Mugambe, Cinzia Digesù, Gabriella Macchia, Solomon Bogale, Mariangela Massaccesi, David Dawotola, Francesco Deodato, Milly Buwenge, Luciana Caravatta, Angelo Piermattei, Vincenzo Valentini, Alessio G Morganti   +12 more
doaj   +1 more source

Clinical implications of the anisotropic analytical algorithm for IMRT treatment planning and verification [PDF]

, 2008
PURPOSE: To determine the implications of the use of the Anisotropic Analytical Algorithm(AAA) for the production and dosimetric verification of IMRT plans for treatments of the prostate, parotid, nasopharynx and lung.
Bragg, C.M., Wingate, K., Conway, J.
core   +1 more source

Dysphagia-optimised intensity-modulated radiotherapy versus standard intensity-modulated radiotherapy in patients with head and neck cancer (DARS): a phase 3, multicentre, randomised, controlled trial.

The Lancet Oncology, 2023
C. Nutting, Laura Finneran, J. Roe, M. Sydenham, M. Beasley, S. Bhide, C. Boon, A. Cook, E. de Winton, M. Emson, B. Foran, R. Frogley, I. Petkar, L. Pettit, K. Rooney, T. Roques, D. Srinivasan, Justine Tyler, E. Hall   +18 more
semanticscholar   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Implementation of Aperture-Based Complexity Metrics of MLC Opening based on the IMRT Technique for Central Nervous System (CNS) and Breast cases [PDF]

Iranian Journal of Medical Physics
Introduction: Complexity metrics have been suggested to characterize treatment plans based on machine parameters such as multileaf collimator (MLC) position.
Meirisa Ambalinggi, Aloysius Putranto, Dewa Prasada, Ida Ayu Gayatri, Supriyanto Pawiro, Dwi Seno Kuncoro Sihono   +5 more
doaj   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

A GPU-based multi-criteria optimization algorithm for HDR brachytherapy

, 2019
Currently in HDR brachytherapy planning, a manual fine-tuning of an objective function is necessary to obtain case-specific valid plans. This study intends to facilitate this process by proposing a patient-specific inverse planning algorithm for HDR ...
Beaulieu, Luc, Bélanger, Cédric, Cui, Songye, Cunha, J. Adam M., Després, Philippe, Ma, Yunzhi   +5 more
core   +2 more sources