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Commissioning of intensity modulated neutron radiotherapy (IMNRT)
Medical Physics, 2013Intensity modulated neutron radiotherapy (IMNRT) has been developed using inhouse treatment planning and delivery systems at the Karmanos Cancer Center∕Wayne State University Fast Neutron Therapy facility. The process of commissioning IMNRT for clinical use is presented here. Results of commissioning tests are provided including validation measurements
Michael Snyder+7 more
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Head and Neck, 2018
To analyze the long‐term outcome and pattern of failure for patients with nasopharyngeal carcinoma (NPC) after intensity‐modulated radiotherapy (IMRT).
Yun-Ming Tian+9 more
semanticscholar +1 more source
To analyze the long‐term outcome and pattern of failure for patients with nasopharyngeal carcinoma (NPC) after intensity‐modulated radiotherapy (IMRT).
Yun-Ming Tian+9 more
semanticscholar +1 more source
Head & Neck, 2016
AbstractBackgroundModern techniques of radiotherapy are supposed to decrease the incidence of osteoradionecrosis of the mandible (ORNM). The purpose of this study was to compare the incidence of ORNM after intensity‐modulated radiotherapy (IMRT) in comparison to conventional 3D conformal radiotherapy techniques (conventional RT).MethodsWe conducted a ...
Maesschalck, Thibault De+7 more
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AbstractBackgroundModern techniques of radiotherapy are supposed to decrease the incidence of osteoradionecrosis of the mandible (ORNM). The purpose of this study was to compare the incidence of ORNM after intensity‐modulated radiotherapy (IMRT) in comparison to conventional 3D conformal radiotherapy techniques (conventional RT).MethodsWe conducted a ...
Maesschalck, Thibault De+7 more
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Regularization of inverse planning for intensity-modulated radiotherapy
Medical Physics, 2005The performance of a variational regularization technique to improve robustness of inverse treatment planning for intensity modulated radiotherapy is analyzed and tested. Inverse treatment planning is based on the numerical solutions to the Fredholm integral equation of the first kind which is ill-posed.
Timothy J. Kinsella+3 more
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Hardware-sensitive optimization for intensity modulated radiotherapy [PDF]
The multileaf collimator (MLC) hardware constraints are usually neglected in the process of intensity-modulated beam optimization. Consequently, it is not always possible to deliver planned beam modulation using dynamic MLC. Beam optimization is significantly diminished if the results must be approximated due to limitations imposed by the delivery ...
Robert J. Marks, Paul S. Cho
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Optimizing the planning of intensity-modulated radiotherapy
Physics in Medicine and Biology, 1994A method of computing optimized intensity-modulated beam profiles has been further developed and used to generate highly conformal radiotherapy dose distributions. The features of these distributions are shown to be strongly dependent on the tuning built into the algorithm.
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Quality assurance of intensity-modulated radiotherapy
Seminars in Radiation Oncology, 2002Intensity-modulated radiation therapy (IMRT) requires the use of inverse treatment planning and nonuniform fluence beams delivered by a series of complex radiation portals. The quality assurance procedures for conventional three-dimensional conformal radiation therapy (3D-CRT) have been developed and are in worldwide clinical use, but the more complex ...
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Energy- and intensity-modulated electron beams for radiotherapy
Physics in Medicine and Biology, 2000This work investigates the feasibility of optimizing energy- and intensity-modulated electron beams for radiation therapy. A multileaf collimator (MLC) specially designed for modulated electron radiotherapy (MERT) was investigated both experimentally and by Monte Carlo simulations.
Edward Mok+8 more
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Head and Neck, 2018
Xerostomia is a debilitating side effect of radiotherapy for head and neck cancer. Combining surgical submandibular‐gland transfer (SMGT) with intensity‐modulated radiotherapy (IMRT) may provide greater protection of salivary function.
R. Scrimger+7 more
semanticscholar +1 more source
Xerostomia is a debilitating side effect of radiotherapy for head and neck cancer. Combining surgical submandibular‐gland transfer (SMGT) with intensity‐modulated radiotherapy (IMRT) may provide greater protection of salivary function.
R. Scrimger+7 more
semanticscholar +1 more source
Submandibular Gland-sparing Intensity-modulated Radiotherapy
American Journal of Clinical Oncology, 2014Xerostomia is one of the most debilitating late effects of head and neck radiotherapy (RT) and significantly impacts quality of life. The submandibular gland (SMG) provides approximately 70% of the unstimulated saliva that accounts for about 95% of the salivary flow during a 24-hour period. Intensity-modulated RT (IMRT) has been used in recent years to
William M. Mendenhall+2 more
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