Results 71 to 80 of about 4,910,060 (313)
К вопросу сейсмического риска территории г. Владикавказ
Геология и геофизика Юга России, 2020 Relevance. The last decades in Russia have been characterized by high growth rates of population, industry, infrastructure in large cities and industrial centers located in seismically active regions.
В. Б. Заалишвили +4 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
CHARACTERISTICS OF HEAVY RAINFALL PARAMETERS IN THE NORTH-WESTERN ROMANIA [PDF]
Aerul şi Apa: Componente ale Mediului, 2011 Characteristics of heavy rainfall parameters in the northwesternRomania. The paper analyzes the frequency, duration, intensity andquantity of heavy rains in north-western Romania, based on data from 14meteorological stations in that area, located in ...
T. TUDOSE, F. MOLDOVAN
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Annual Review of Psychology, 1989 INTRODUCTION 109 POTENTIAL MOTIVATION AND MOTIVATIONAL ROUSAL 110 Potential Motivation 110 Motivational Arousal 111 EVIDENCE ON THE JOINT EFFECTS OF POTENTIAL MOTIVATION AND IFFICULTY 111 Effects on Cardiovascular Reactivity 111 Intended Effort 1 ! 6 Behavioral Effects 117 Subjective Appraisals of Motivational Factors 121 CONCLUSIONS
Brehm, Jack W., Self, Elizabeth A.
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
On the calculation of plates by the series representation of the deflection function
Қарағанды университетінің хабаршысы. Математика сериясы, 2016 In the article calculations of rectangular plates by the series representation of the deflection function are presented. For the considered rectangular plate the investigation was determined by finding the minimum of the potential energy of the plate by
A.S. Ahanova +2 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source