Results 81 to 90 of about 4,130,590 (307)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Réflexions méthodologiques sur l’analyse phonétique d’un corpus longitudinal et transversal en acquisition du langage

open access: yesCorela, 2013
The goal of this study is to see whether children’s level of language development has any effect on the acoustic structure of laughter. A major difficulty lies in the fact that such a study needs to combine both synchronic analyses and a longitudinal ...
Jérémi Sauvage   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Intensity-Modulated Photocurrent Spectroscopy for Solar Energy Conversion Devices: What Does a Negative Value Mean?

open access: yes, 2019
Intensity-Modulated Photocurrent Spectroscopy for Solar Energy Conversion Devices: What Does a Negative Value ...
Miguel García-Tecedor   +11 more
core   +1 more source

The Intensity of Motivation

open access: yesAnnual Review of Psychology, 1989
INTRODUCTION 109 POTENTIAL MOTIVATION AND MOTIVATIONAL ROUSAL 110 Potential Motivation 110 Motivational Arousal 111 EVIDENCE ON THE JOINT EFFECTS OF POTENTIAL MOTIVATION AND IFFICULTY 111 Effects on Cardiovascular Reactivity 111 Intended Effort 1 ! 6 Behavioral Effects 117 Subjective Appraisals of Motivational Factors 121 CONCLUSIONS
Brehm, Jack W., Self, Elizabeth A.
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Intensity-correlated spiking infrared and ultraviolet emission from sodium vapors

open access: yes, 2021
The directional spiking infrared and ultraviolet emission from sodium vapors excited to the 4D5/2 level by a continuous-wave resonant laser pump, that constitute a novel feature of the cooperative effects, has been analyzed.
Felipe Pedreros Bustos (14382186)   +2 more
core   +1 more source

Methodological Approach to Determining Labor Consumption to Perform Scientific-Research Work

open access: yesУчёт. Анализ. Аудит, 2019
Currently organizations of the military-industrial complex do not possess adequate methodological means to draw up an educated position in order to coordinate the labor-output ratio with the experts of the military representative office of the Ministry ...
ALEXANDER G. Podolsky, ALEXEJ V Babkin
doaj   +1 more source

To intensive care or not to intensive care—that is the question

open access: yesEuropean Journal of Cardio-Thoracic Surgery, 2022
Freyja-Maria, Smolle-Juettner   +3 more
openaire   +2 more sources

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