Results 51 to 60 of about 369,043 (263)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
This work presents a new approach for the design of an FMF with a Gaussian core and a trench in the cladding. For the proposed few‐mode fibre (FMF), Fused Silica (SiO2) is considered as a host‐material, whereas Germanium Oxide(GeO2) and Fluorine(F)are ...
Bhagyalaxmi Behera +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The performances comparison of ROF systems based on intensity modulation and phase modulation
According to the researches of transmitting downlink signal based on optical carrier suppression, we demonstrate two different ROF systems, one is based on intensity modulation to suppress the optical carrier, another is using phase modulation to ...
XU Guan +5 more
doaj
Colour-shift keying (CSK) is a visible light communication (VLC) modulation scheme used in the existing IEEE 802.15.7 standard. In CSK, information is transmitted by changing the light intensities of the RGB LEDs.
Roger Alexander Martínez-Ciro +3 more
doaj +1 more source
Compact Low-Loss Electroabsorption Modulator Using a Graphene-Inserted Metal-Slot-Added Waveguide
Metal slots have been used to obtain strong light-graphene interaction, which usually requires them to be a few tens of nanometers wide. However, narrow metal slot waveguides have a large intrinsic loss; they are not efficiently connected to conventional
Jihoon Seo, Min-Suk Kwon
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

