BioengineeringBackground: Whole-Body Diffusion-Weighted Imaging (WBDWI) is an established technique for staging and evaluating treatment response in patients with multiple myeloma (MM) and advanced prostate cancer (APC).
Antonio Candito +6 more
doaj +3 more sources
Modelling inter-individual variability in acute and adaptive responses to interval training: insights into exercise intensity normalisation. [PDF]
Eur J Appl Physiol, 2023 Abstract Purpose To investigate the influence of exercise intensity normalisation on intra- and inter-individual acute and adaptive responses to an interval training programme. Methods Nineteen cyclists were split in two groups differing (only) in how exercise intensity was ...
Bossi AH +3 more
europepmc +3 more sources
Fluorescence intensity normalisation: correcting for time effects in large-scale flow cytometric analysis. [PDF]
Adv Bioinformatics, 2009 A next step to interpret the findings generated by genome-wide association studies is to associate molecular quantitative traits with disease-associated alleles. To this end, researchers are linking disease risk alleles with gene expression quantitative trait loci (eQTL). However, gene expression at the mRNA level is only an intermediate trait and flow
Dendrou CA +5 more
europepmc +5 more sources
Early intensive treatment normalises excess mortality in ACPA-negative RA but not in ACPA-positive RA [PDF]
Annals of the Rheumatic Diseases, 2020 With great interest, we read the recently published report by Poppelaars et al in which no excess mortality was observed in 155 patients with rheumatoid arthritis (RA) from the COmbinatie therapie Bij Rheumatoide Artritis (COBRA)-trial, who received early intensive treatment, compared with the general population (Standardised mortality rate (SMR) 0.80 (
Matthijssen, X.M.E. +3 more
openaire +4 more sources
Nonparametric Density Flows for MRI Intensity Normalisation [PDF]
, 2018 Accepted for publication at MICCAI ...
Daniel Coelho de Castro, Ben Glocker
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Mortality has improved in RA, but we must remain vigilant. Response to: ‘Early intensive treatment normalises excess mortality in ACPA-negative RA but not in ACPA-positive RA’ by Matthijssen et al [PDF]
Annals of the Rheumatic Diseases, 2020 We compliment Matthijssen et al with this highly interesting analysis and results from the Leiden Early Arthritis Clinic. Their mortality results strongly support our findings1 and again emphasise that the focus should be on the excess mortality that emerges after 10 years.
Pomme B M Poppelaars +2 more
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Italian Journal of Animal Science, 2010 Four different normalisation techniques were applied for the corrections of fluorescence data generated by a cDNA microarray experiment. Correction for inaccurate signals and possible bias induced by fluorescence intensity, background intensity and dye ...
N. P. P. Macciotta +2 more
doaj +1 more source
Characterising the space–time structure of rainfall in the Sahel with a view to estimating IDAF curves [PDF]
Hydrology and Earth System Sciences, 2014 Intensity–duration–area–frequency (IDAF) curves are increasingly demanded for characterising the severity of storms and for designing hydraulic structures.
G. Panthou +4 more
doaj +1 more source
Atmospheric Science Letters, 2022 Europe has been affected by record‐breaking heat waves in recent decades. Using station data and a gridded reanalysis as input, four commonly used heat wave indices, the heat wave magnitude index daily (HWMId), excess heat factor (EHF), wet‐bulb globe ...
Florian N. Becker +3 more
doaj +1 more source
Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major [PDF]
British Journal of Haematology, 2010 SummaryCardiac and endocrine disorders are common sequelae of iron overload in transfused thalassaemia patients. Combined chelation with desferrioxamine (DFO) and deferiprone (DFP) is well tolerated and produces an additive/synergistic effect superior to either drug alone.
Farmaki, K. +4 more
openaire +3 more sources