Results 41 to 50 of about 16,736 (246)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

From Stability to Escalation: Temporal Dynamics of Discursive Risk in NATO’s Facebook Communication on the Ukraine–Russia War

Social Sciences
This article examines how NATO adapted its public communication during the 2022–2025 Ukraine–Russia war by analysing over 1400 Facebook posts through an integrated interpretive–computational approach.
Tanase Tasente, Mihaela Rus, Mihai Stefanoaia, Mihaela Luminita Sandu   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

A Randomised, Controlled Study of Different Glycaemic Targets during Gestational Diabetes Treatment: Effect on the Level of Adipokines in Cord Blood and ANGPTL4 Expression in Human Umbilical Vein Endothelial Cells

International Journal of Endocrinology, 2018
Our aim was to study the expression of adipokine-encoding genes (leptin, adiponectin, and angiopoietin-like protein 4 (ANGPTL4)) in human umbilical vein endothelial cells (HUVECs) and adipokine concentration in cord blood from women with gestational ...
P. Popova, L. Vasilyeva, A. Tkachuck, M. Puzanov, A. Golovkin, Y. Bolotko, E. Pustozerov, E. Vasilyeva, O. Li, I. Zazerskaya, R. Dmitrieva, A. Kostareva, E. Grineva   +12 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Intrinsic noise of a superheated droplet detector for neutron background measurements in massively shielded facilities

EPJ Web of Conferences, 2017
Superheated droplet detectors are a promising technique to the measurement of low-intensity neutron fields, as detectors can be rendered insensitive to minimum ionizing radiations.
Fernandes Ana C., Morlat Tomoko A., Felizardo Miguel, Kling Andreas, Marques José G., Prudêncio Maria I., Marques Rosa, Carvalho Fernando P., Roche Ignácio Lázaro, Girard Thomas A.   +9 more
doaj   +1 more source

Comparison of strategies for monitoring and treating patients at the early phase of severe traumatic brain injury: the multicentre randomised controlled OXY-TC trial study protocol

BMJ Open, 2020
Introduction Intracranial hypertension is considered as an independent risk factor of mortality and neurological disabilities after severe traumatic brain injury (TBI).
Nicolas Bruder, Thomas Geeraerts, Jean Luc Bosson, Claire Dahyot-fizelier, Pierre Bouzat, Jean-François Payen, Laurent Gergelé, Gérard Audibert, Louis Puybasset, Marion Richard, Gilles Francony, Emmanuel L Barbier, Bernard Vigue, Kristina Skaare   +13 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Standardized volumetric 3D-analysis of SPECT/CT imaging in orthopaedics: overcoming the limitations of qualitative 2D analysis

BMC Medical Imaging, 2012
Background SPECT/CT combines high resolution anatomical 3D computerized tomography (CT) and single photon emission computerized tomography (SPECT) as functional imaging, which provides 3D information about biological processes into a single imaging ...
Hirschmann Michael T, Wagner Christopher R, Rasch Helmut, Henckel Johann   +3 more
doaj   +1 more source