Results 121 to 130 of about 213,172 (305)

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park   +7 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Towards Skillful Tropical Cyclone Forecasting by AI‐Model‐Driven High‐Resolution Regional Coupled Model

open access: yesMeteorological Applications
With the recent rise of artificial intelligence (AI), data‐driven global weather forecasting models have demonstrated superior performance compared to state‐of‐the‐art physics‐based global models across various weather elements.
Sin Ki Lai   +5 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

Development of FPGA controlled diagnostics on the MAST fusion reactor [PDF]

open access: yes, 2013
Field Programmable Gate Array technology (FPGA) is very useful for implementing high performance digital signal processing algorithms, data acquisition and real-time control on nuclear fusion devices.
HUANG, BILLY,KIAT
core  

Consistency of intensity ratio between spectral lines with similar self-absorption characteristics during ungated laser induced breakdown spectroscopy measurements

open access: yes, 2019
This work reports that the intensity ratio of spectral lines having similar self-absorption characteristics during laser induced breakdown spectroscopy (LIBS) analysis can become nearly constant over a wide range of irradiation conditions if the ...
In, Jung-Hwan   +3 more
core   +1 more source

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier   +6 more
wiley   +1 more source

Intensity or volume: the role of physical activity in longevity

open access: yesEuropean Journal of Preventive Cardiology
Abstract Aims To investigate how physical activity (PA) volume, intensity, duration, and fragmentation are associated with the risk of all-cause and cardiovascular disease mortality. To produce centile curves for PA volume and intensity representative of US adults.
Fabian Schwendinger   +6 more
openaire   +2 more sources

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

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