Results 121 to 130 of about 321,086 (317)

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

Advanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong, Shanshan Dai, Fan Yu, Guo‐Ping Shi, Qinyan Gong, Yucong Zhang, Jingsi Duan, Zhengyin Lou, Zhixuan Tang, Fuzhe Gong, Derong Chen, Liya Hou, Xinyang Hu, Jinghai Chen, Jian'an Wang, Deling Yin   +15 more
wiley   +1 more source

Facilitating change and evaluating impact during a neonatal intensive care redevelopment: A participatory action research project [PDF]

, 2016
There have been many reports indicating that if the design of Neonatal Intensive Care Units provides neonates with a more developmentally appropriate environment during the period of their admission, there would be significant neurodevelopmental benefits.
Broom, Margaret
core   +1 more source

Floppy Infant Syndrome: new approach to the study of neonatal hypotonia through the analysis of a rare case of X-Linked Myotubular Myopathy

Journal of Pediatric and Neonatal Individualized Medicine, 2014
The Floppy Infant Syndrome includes a variety of signs and symptoms: decrease in muscle tone (hypotonia), in muscle power (weakness) and ligamentous laxity and increased range of joint mobility.
Massimiliano De Vivo, Silvana Rojo, Roberto Rosso, Giovanni Chello, Paolo Giliberti   +4 more
doaj   +1 more source

Postoperative brain volumes are associated with one-year neurodevelopmental outcome in children with severe congenital heart disease [PDF]

arXiv, 2019
Children with congenital heart disease (CHD) remain at risk for neurodevelopmental impairment despite improved peri- and intraoperative care. Our prospective cohort study aimed to determine the relationship between perioperative brain volumes and neurodevelopmental outcome in neonates with severe CHD. Pre- and postoperative cerebral MRI was acquired in
arxiv  

LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation

Advanced Science, EarlyView.
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao, Chao Yan, Haibo Huang, Shilong Wang, Jiaying Li, Yun Chen, Xiaolu Qu, Qi Bao, Lingna Xu, Yuanyuan Zhang, Danyang Fan, Xia He, Yanwen Liu, Yongsheng Zhang, Yalan Yang, Zhonglin Tang   +15 more
wiley   +1 more source

Case histories of five years of neonatal urinary tract infections: practical aspects of treatment and the need for agreed-upon guidelines

Journal of Pediatric and Neonatal Individualized Medicine, 2012
Case series of urinary tract infection (UTI) in neonates (0 to 1 month of life) hospitalized in the neonatal care unit of Cagliari’s university hospital during a five-year period.
Giovanni Ottonello, Angelica Dessì, Giuseppe Masnata, Marcella Peri, Alice Melis, Vassilios Fanos   +5 more
doaj   +1 more source

Deep learning in the ultrasound evaluation of neonatal respiratory status [PDF]

arXiv, 2020
Lung ultrasound imaging is reaching growing interest from the scientific community. On one side, thanks to its harmlessness and high descriptive power, this kind of diagnostic imaging has been largely adopted in sensitive applications, like the diagnosis and follow-up of preterm newborns in neonatal intensive care units. On the other side, state-of-the-
arxiv  

Microglial MS4A4A Protects against Epileptic Seizures in Alzheimer's Disease

Advanced Science, EarlyView.
This study has unveiled significant new insights into the role of MS4A4A in Alzheimer's disease‐related epilepsy, highlighting its impact on microglial phagocytosis, mitochondrial metabolism, and cytoskeleton, and demonstrating its therapeutic potential in epilepsy management.
Meng Jiang, Qingqing Li, Jianhui Chen, Ruochong Li, Jun Yao, Yong Hu, Haizheng Zhang, Lixin Cai, Maoguo Luo, Yu Sun, Wenwen Zeng   +10 more
wiley   +1 more source

Using the Delphi technique to develop standards for neonatal intensive care nursing education [PDF]

, 2011
The purpose of this study was to use the Delphi technique to determine the first draft of national standards for neonatal intensive care nursing (NICN) education.
Mannix, Trudi Gaye
core  

Respiratory Care Protocols in Neonatal Intensive Care [PDF]

, 2016
Neonatal respiratory care involves physicians with variable backgrounds treating multiple respiratory problems and populations with a number of invasive and non-invasive devices and strategies.
Anna, Guilherme Mendes Sant’, Shalish, Wissam   +1 more
core   +2 more sources