Results 61 to 70 of about 2,528,189 (360)

Working in the Neonatal Intensive Care Unit Is More Than Saving a Baby’s Life [PDF]

, 2022
Godbless M. Philipo, Hannah Lee
openalex   +1 more source

Psychiatric nurses’ views on criteria for psychiatric intensive care: acute and intensive care staff compared [PDF]

, 2003
Aim: To explore and investigate differences between the views of qualified nurses working in psychiatric intensive care units (PICUs) and acute care wards on which patients are appropriate for PICU care.
Allan, Basson, Beer, Brown, Clark, Dix, Eddie McCann, Holzworth, Jane Alexander, Jeffery, Lehane, Len Bowers, Michalon, Neil Crowhurst, Rachlin, Ryan, Sarah Eales, Smith, Stuart Guy, Werner   +19 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Origins of neonatal intensive care in the UK [PDF]

, 2001
Chaired by Professor Robert Boyd, this seminar reviewed the development and changes in care of the newborn in the UK over the past 50 years. Advances in techniques were described, such as mechanical ventilation, total parenteral nutrition and continuous ...

core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

A Subtle Presentation of Pharyngitis and Pneumonia: Lemierre Syndrome

Case Reports in Pulmonology
Lemierre syndrome (LS) is a rare condition with an estimated incidence of 1–10/1,000,000 per year defined as a complication of an oral and nasopharyngeal infection with secondary septicemia leading to septic emboli and internal jugular vein thrombosis ...
Federico Bellini, Valentino Allocca, Laura Aspidistria, Marco Farinatti, Ippolito Guzzinati, Marta Maria Daniele, Serena Casanova, Francesca Gasparini, Mara Nalin, Sara Saturni, Gian Luca Casoni   +10 more
doaj   +1 more source

Expertise and the interpretation of computerized physiological data: implications for the design of computerized monitoring in neonatal intensive care [PDF]

, 2001
This paper presents the outcomes from a cognitive engineering project addressing the design problems of computerized monitoring in neonatal intensive care.
ALBERDI, ALBERDI, ALBERDI, ANDY LYON, AZEVEDO, BARNARD, BOSHUIZEN, CARD, CARROLL, CHASE, CHI, CLAESSEN, COIERA, COIERA, COIERA, CUNNINGHAM, CUNNINGHAM, DEERE, EDWORTHY, EGAN, ELSTEIN, ELSTEIN, ERICSSON, ERICSSON, ERICSSON, ERICSSON, EUGENIO ALBERDI, FELTOVICH, FELTOVICH, GILHOOLY, GILHOOLY, GRAY, GREEN, GREEN, GREMY, HAIMOWITZ, JAN REISS, JIM HUNTER, JOSEPH, JULIE-CLARE BECHER, KEN GILHOOLY, LANDAUER, LARKIN, LARKIN, LEMIEUX, LESGOLD, LESGOLD, LOGIE, LONG, LONG, MCINTOSH, MORGAN, NEIL MCINTOSH, NENOV, NORMAN, PATEL, PATEL, PATEL, PATEL, PATEL, ROBERT LOGIE, SALATIAN, SCHMIDT, SCHMIDT, TABOADA, WICKENS   +65 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Esophageal Achalasia: An Unusual Cause of Respiratory Distress

Case Reports in Critical Care
Esophageal achalasia is a rare condition affecting both men and women. It is a motility disorder of the esophagus resulting in the lack of relaxation of the lower sphincter, yielding to food stasis.
Océane Thiry, Marion Schaefer, Aurélie Cravoisy, Lionel Nace, Thibault François, Jacques Allard, Sébastien Gibot   +6 more
doaj   +1 more source