Results 91 to 100 of about 2,158,632 (410)

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1422-1435, May 2025.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

Hypercapnia from Physiology to Practice

open access: yesInternational Journal of Clinical Practice, 2022
Acute hypercapnic ventilatory failure is becoming more frequent in critically ill patients. Hypercapnia is the elevation in the partial pressure of carbon dioxide (PaCO2) above 45 mmHg in the bloodstream.
Amilkar Almanza-Hurtado   +5 more
doaj   +1 more source

Psychiatric intensive care nursing - psychoanalytic perspectives [PDF]

open access: yes, 1998
Based on unobtrusive observations a parallel is drawn between general and psychiatric intensive care milieu. The correlation between the bedside skills and incidence of phyical contact is considered in each setting.
Winship, G.
core   +1 more source

Delirium in the intensive care unit [PDF]

open access: yesCritical Care, 2008
Delirium, an acute and fluctuating disturbance of consciousness and cognition, is a common manifestation of acute brain dysfunction in critically ill patients, occurring in up to 80% of the sickest intensive care unit (ICU) populations. Critically ill patients are subject to numerous risk factors for delirium.
E. Wesley Ely   +3 more
openaire   +3 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1386-1403, May 2025.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Neuroprem: the Neuro-developmental outcome of very low birth weight infants in an Italian region

open access: yesItalian Journal of Pediatrics, 2020
Introduction The survival of preterm babies has increased worldwide, but the risk of neuro-developmental disabilities remains high, which is of concern to both the public and professionals.
Licia Lugli   +36 more
doaj   +1 more source

Explaining anomalous responses to treatment in the Intensive Care Unit [PDF]

open access: yes, 2009
The Intensive Care Unit (ICU) provides treatment to critically ill patients. When a patient does not respond as expected to such treatment it can be challenging for clinicians, especially junior clinicians, as they may not have the relevant experience to
Booth, M.   +8 more
core   +1 more source

Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit

open access: yesOpen Forum Infectious Diseases, 2018
Background There is a need to better define the epidemiology of sepsis in intensive care units (ICUs) around the globe. Methods The Intensive Care over Nations (ICON) audit prospectively collected data on all adult (>16 years) patients admitted to the ...
Y. Sakr   +9 more
semanticscholar   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

A Subtle Presentation of Pharyngitis and Pneumonia: Lemierre Syndrome

open access: yesCase Reports in Pulmonology
Lemierre syndrome (LS) is a rare condition with an estimated incidence of 1–10/1,000,000 per year defined as a complication of an oral and nasopharyngeal infection with secondary septicemia leading to septic emboli and internal jugular vein thrombosis ...
Federico Bellini   +10 more
doaj   +1 more source

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