Results 101 to 110 of about 2,122,051 (402)

Hyperglycemia in the Intensive Care Unit

Türk Yoğun Bakim Derneği Dergisi, 2014
Hyperglycemia is frequently encountered in the intensive care unit. In this disease, after severe injury and during diabetes mellitus homeostasis is impaired; hyperglycemia, hypoglycemia and glycemic variability may ensue.
Rainer Lenhardt, Ozan Akca
doaj   +1 more source

A preliminary study of intensivist-performed DVT ultrasound screening in trauma ICU patients (APSIT Study)

Annals of Intensive Care, 2020
Background Multiple screening Duplex ultrasound scans (DUS) are performed in trauma patients at high risk of deep vein thrombosis (DVT) in the intensive care unit (ICU). Intensive care physician performed compression ultrasound (IP-CUS) has shown promise
Lloyd Roberts, Tom Rozen, Deirdre Murphy, Adam Lawler, Mark Fitzgerald, Harry Gibbs, Kyle Brooks, Joshua F. Ihle, Tim Leong, Judit Orosz, Eldho Paul, Vinodh Bhagyalakshmi Nanjayya   +11 more
doaj   +1 more source

Suppression of lncRNA OIP5-AS1 Attenuates Apoptosis and Inflammation, and Promotes Proliferation by Mediating miR-25-3p Expression in Lipopolysaccharide-Induced Myocardial Injury

Analytical Cellular Pathology, 2023
Purpose. Long non-coding RNAs (LncRNAs) OIP5-AS1 and miR-25-3p play important roles in myocardial injury, whereas their roles in lipopolysaccharide (LPS)-induced myocardial injury remain unknown. The purpose of our study was to investigate the functional
Jiaju Ma, Hebu Qian, Han Zou
doaj   +1 more source

Clinical Use of EEG in the ICU: Technical Setting. [PDF]

, 2015
Neurophysiology is an essential tool for clinicians dealing with patients in the intensive care unit. Because of consciousness disorders, clinical examination is frequently limited.
Alvarez, V., Rossetti, A.O.
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Physiotherapy in the intensive care unit [PDF]

Southern African Journal of Critical Care, 2016
No ...
openaire   +5 more sources

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

The Royal Free Hospital score: a calibrated prognostic model for patients with cirrhosis admitted to intensive care unit. Comparison with current models and CLIF-SOFA score [PDF]

, 2014
Prognosis for patients with cirrhosis admitted to intensive care unit (ICU) is poor. ICU prognostic models are more accurate than liver-specific models.
Agarwal, B, Burroughs, AK, Cheung, M, Cholongitas, E, Mohammad, AO, Pieri, G, Theocharidou, E   +6 more
core   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Critical Care Nursing Interventions and Incidence of Ventilator Associated Pneumonia in the Trauma Population [PDF]

, 2012
Ventilator Associated Pneumonia (VAP) in the Trauma Intensive Care Unit is the most commonly encountered infection in the intensive care unit and can be linked to increased morbidity, increased mortality, increased mechanical ventilation days, increased ...
Moore, Kelli R.
core   +1 more source