Results 131 to 140 of about 2,158,632 (410)

Assessment of fluid responsiveness in spontaneously breathing patients: a systematic review of literature

open access: yesAnnals of Intensive Care, 2018
Patients who increase stoke volume or cardiac index more than 10 or 15% after a fluid challenge are usually considered fluid responders. Assessment of fluid responsiveness prior to volume expansion is critical to avoid fluid overload, which has been ...
Renato Carneiro de Freitas Chaves   +7 more
doaj   +1 more source

ICU delirium - a diagnostic and therapeutic challenge in the intensive care unit.

open access: yesAnaesthesiology Intensive Therapy, 2018
ICU delirium is a common medical problem occurring in patients admitted to the intensive care units (ICUs). Studies have shown that ICU delirium is associated with increased mortality, prolonged hospitalization, prolonged mechanical ventilation, costs ...
K. Kotfis, A. Marra, E. W. Ely
semanticscholar   +1 more source

Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy.

open access: yesJAMA Internal Medicine, 2020
Importance Many patients with coronavirus disease 2019 (COVID-19) are critically ill and require care in the intensive care unit (ICU). Objective To evaluate the independent risk factors associated with mortality of patients with COVID-19 requiring ...
G. Grasselli   +147 more
semanticscholar   +1 more source

Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao   +4 more
wiley   +1 more source

Update of Sepsis in the Intensive Care Unit

open access: yesJournal of Innate Immunity, 2017
Sepsis, the most common cause of admission to an intensive care unit (ICU), has had an increased incidence and prevalence over the last years with a simultaneous decrease in its short-term mortality.
K. Genga, J. Russell
semanticscholar   +1 more source

Thrombocytopenia in Intensive Care Unit

open access: yesIndian Journal of Critical Care Medicine, 2019
How to cite this article: Aluru N, Samavedam S. Thrombocytopenia in Intensive Care Unit. Indian J Crit Care Med 2019;23(Suppl 3):S185-S188.
Srinivas Samavedam, Narmada Aluru
openaire   +2 more sources

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

Development of Prone Position Ventilation Device and Study on the Application Effect of Combined Life Support Technology in Critically Ill Patients

open access: yesCanadian Respiratory Journal
Objective. This study aims to evaluate a novel prone position ventilation device designed to enhance patient safety, improve comfort, and reduce adverse events, facilitating prolonged tolerance in critically ill patients. Methods. A randomized controlled
Yufeng Li   +7 more
doaj   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

Evaluation of CD4+ T Lymphocyte Counts to Predict Survival of ICU Patients with Sepsis Using Sepsis-3 Criteria: A Prospective Cohort Study

open access: yesEmergency Medicine International
Background. Sepsis remains a major health condition with a high mortality rate that may be related to immunosuppression. T lymphocyte subsets may reflect the immune function of sepsis patients.
Guoge Huang   +10 more
doaj   +1 more source

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