Results 81 to 90 of about 2,077,324 (384)
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit
Open Forum Infectious Diseases, 2018 Background There is a need to better define the epidemiology of sepsis in intensive care units (ICUs) around the globe. Methods The Intensive Care over Nations (ICON) audit prospectively collected data on all adult (>16 years) patients admitted to the ...
Y. Sakr +9 more
semanticscholar +1 more source
Explaining anomalous responses to treatment in the Intensive Care Unit [PDF]
, 2009 The Intensive Care Unit (ICU) provides treatment to critically ill patients. When a patient does not respond as expected to such treatment it can be challenging for clinicians, especially junior clinicians, as they may not have the relevant experience to
Booth, M. +8 more
core +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Family care in intensive care units
Southern African Journal of Critical Care, 2019 No Abstract.
openaire +6 more sources
A Subtle Presentation of Pharyngitis and Pneumonia: Lemierre Syndrome
Case Reports in PulmonologyLemierre syndrome (LS) is a rare condition with an estimated incidence of 1–10/1,000,000 per year defined as a complication of an oral and nasopharyngeal infection with secondary septicemia leading to septic emboli and internal jugular vein thrombosis ...
Federico Bellini +10 more
doaj +1 more source
Hypercapnia from Physiology to Practice
International Journal of Clinical Practice, 2022 Acute hypercapnic ventilatory failure is becoming more frequent in critically ill patients. Hypercapnia is the elevation in the partial pressure of carbon dioxide (PaCO2) above 45 mmHg in the bloodstream.
Amilkar Almanza-Hurtado +5 more
doaj +1 more source
Predicting Intensive Care Unit Readmission with Machine Learning Using Electronic Health Record Data
Annals of the American Thoracic Society, 2018 &NA; Rationale: Patients transferred from the intensive care unit to the wards who are later readmitted to the intensive care unit have increased length of stay, healthcare expenditure, and mortality compared with those who are never readmitted ...
J. C. Rojas +5 more
semanticscholar +1 more source
Post-Intensive Care Unit Psychiatric Comorbidity and Quality of Life [PDF]
, 2017 The prevalence of psychiatric symptoms ranges from 17% to 44% in intensive care unit (ICU) survivors. The relationship between the comorbidity of psychiatric symptoms and quality of life (QoL) in ICU survivors has not been carefully examined.
Boustani, Malaz +7 more
core +1 more source
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source