Results 61 to 70 of about 1,093,914 (301)

UCH-L1 Inhibitor Alleviates Nerve Damage Caused by Moyamoya Disease

Applied Bionics and Biomechanics
Background. Moyamoya disease (MMD) leads to nerve injury. Exosomes are touted as bio-shuttles for the delivery of distinct biomolecules inside the cells. Recently, UCH-L1 was shown to play a vital role in nerve injury.
Minghua Xu, Xiaomin Zhao, Jiang Zhao, Zhisheng Tan, Chengshi Zhang, Yun Huang, Huiping Zhong, Meifeng Guo, Chen Zhang, Ping Ye, Wentao Zheng   +10 more
doaj   +1 more source

Control of an outbreak of carbapenem-resistant Acinetobacter baumannii in Australia after introduction of environmental cleaning with a commercial oxidizing disinfectant [PDF]

, 2010
In the midst of an outbreak, carbapenem-resistant Acinetobacter baumannii was grown from samples of multiple environmental sites in an intensive care unit.
Anthony M. Allworth, David L. Paterson, Graeme R. Nimmo, Hernndez, Hwee Mian Goh, Jeffrey Lipman, Kathryn O'Brien, Marion Woods, Mark A. Schembri, Michael Terry, Michelle Doidge, Narelle George, Penelope Marshall, Tenover   +13 more
core   +1 more source

Severe and refractory anaphylaxis in pediatric intensive care unit [PDF]

, 2023
Guillaume Pouessel, Capucine Trochu, Flore Chagnon, Rémy Diesnis, Stéphane Leteurtre, A. Deschildre, the French Group for Paediatric Intensive Care and Emergencies (FGPICE)   +6 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Diabetic Ketoacidosis (DKA) Insulin Infusion Protocol Update Using Evidence-Based Practice: A Quality Improvement Project [PDF]

, 2018
Diabetic Ketoacidosis is a life-threatening side effect to Diabetes Mellitus. Standards of treatment and recommendations are made by the American Diabetes Association.
Lacey, Susan K
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Infant/Early Childhood Mental Health and Collaborative Partnerships: Beyond the NICU [PDF]

, 2016
The NICU experience impacts all family dynamics not just during the intensive care unit stay but in the months and years afterwards. For each family, the first experiences with their baby, whether in the home or the intensive care unit, can set the ...
Deloian, Barbara, Tomlin, Angela M., Wollesen, Linda   +2 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Successful Management of Extreme Hyperglycemia (134 mmol/L) Secondary to Chronic Pancreatitis Causing Critical Hyperosmolar Coma: A Case Report

Case Reports in Endocrinology
Hyperosmolar hyperglycemic state (HHS) is a life-threatening condition characterized by extreme hyperglycemia, high plasma osmolality, and severe dehydration without significant ketoacidosis.
Arnaud Robert, Sandra Ihirwe Habineza, David Leng, Chloé Dieudonné, Patrick M. Honoré, Pierre Bulpa   +5 more
doaj   +1 more source

Managing malaria in the intensive care unit. [PDF]

, 2014
The number of people travelling to malaria-endemic countries continues to increase, and malaria remains the commonest cause of serious imported infection in non-endemic areas.
Doherty, JF, Gupta-Wright, A, Marks, M, Singer, M, Walker, D   +4 more
core   +1 more source