Results 61 to 70 of about 608,841 (219)

Latent profiles of compassion fatigue among clinical nurse preceptors and their associations with work alienation

Scientific Reports
This study aimed to investigate the latent profiles of clinical nurse preceptors (CNPs)’ compassion fatigue (CF), identify the influencing factors, and examine their association with work alienation.
Yuejun Huang, Han Zhang, Yu Chen, Zhaojun Xu   +3 more
doaj   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera, Agnese Tamanti, Silvia Messina, Nicola Dall'Osto, Teresa Maltempo, Stefano Ziccardi, Matteo Foschi, Maria Grazia Piscaglia, Diana Ferraro, Francesco Crescenzo, Francesca Rossi, Albulena Bajrami, Sabrina Marangoni, Damiano Marastoni, Francesca Benedetta Pizzini, Maria Isabel Leite, Roberta Magliozzi, Patrick Waters, Massimiliano Calabrese, Jacqueline Palace, Ruth Geraldes   +20 more
wiley   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Integration of Diaphragmatic Ultrasonography and Intra-Abdominal Pressure Measurement for Optimizing Weaning from Mechanical Ventilation

Risk Management and Healthcare Policy
Dan Su,1,* Ruixin Li,1,* Zhi Chen,2 Na Cui,1 Zhanbiao Yu,1 Xiaoxu Ding,1 Jiaqian Wu1 1Intensive Care Unit, The Affiliated Hospital of Hebei University, Baoding, Hebei Province, 071000, People’s Republic of China; 2Department of ...
Su D, Li R, Chen Z, Cui N, Yu Z, Ding X, Wu J   +6 more
doaj  

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Knowledge, Attitude, and Practice of Thrombolysis in Family Members of Cerebral Infarction Patients: Structural Equation Modeling Analysis

International Journal of General Medicine
Fan Huang,1,2 Ling Zhou,1,2 Ping Zhao,1,2 Meiping Guo,1,2 Wujia Chen1,2 1Intensive Care Unit, Wujin Hospital Affiliated with Jiangsu University, Changzhou, 213000, People’s Republic of China; 2The Wujin Clinical College of Xuzhou Medical University ...
Huang F, Zhou L, Zhao P, Guo M, Chen W
doaj  

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Multivariate Analysis of Shock Risk and Model Development and Validation in Elderly Patients Following Hip Fracture Surgery in the Intensive Care Unit (ICU): A Retrospective Cohort Study

Clinical Interventions in Aging
Xue Wang, Zhen Cui, Mengqi Tong, Miaomiao Yu, Ying Bai Department of Critical Care Medicine, Beijing Jishuitan Hospital Affiliated to Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Ying Bai, Department of ...
Wang X, Cui Z, Tong M, Yu M, Bai Y
doaj  

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Clinically Suspected Whipple Disease Presenting with Acute Kidney Injury as the Initial Manifestation and Complicated by Severe Pneumonia Requiring Veno-Venous Extracorporeal Membrane Oxygenation

Infection and Drug Resistance
Li-Juan Duan,* Bing Feng,* Jia-Ding Xia, Jing-Yuan Zhao, Kun Zhang Department of Intensive Care Unit, Affiliated Hospital of Chengde Medical University, Chengde, Hebei, 067000, People’s Republic of China*These authors contributed ...
Duan LJ, Feng B, Xia JD, Zhao JY, Zhang K   +4 more
doaj