Results 51 to 60 of about 6,984,190 (307)
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
The prevalence and effects of HIV infection among a population of pregnant women needing obstetric intensive care in Cape Town [PDF]
, 2010 Includes bibliographical references (leaves 36-37).Care of the critically ill pregnant woman poses exceptional challenges in the intensive care unit and requires the skills of health care providers who have knowledge of the physiological changes of ...
Mohlaba, Garish Masungi
core +1 more source
The Effectiveness of Bevacizumab in COVID-19 Pneumonia Among Critically Ill Patients
Egyptian Journal of Critical Care Medicine, 2022 Background Bevacizumab, an antiangiogenic drug, is being evaluated for the management of novel coronavirus disease (COVID-19) pneumonia among critically ill patients.
Karthikkeyan Rajachandran +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Determining the Difficulties of Parents with Children in Home Care Who Were Discharged from Intensive Care [PDF]
Introduction: This study was performed to determine the difficulties experienced by parents with children in home care who were discharged from intensive care.
Gülzade Uysal +4 more
core +1 more source
Critical Care, 2017 Background Left ventricular diastolic dysfunction is associated with mortality outcomes in severe sepsis and septic shock. There are ongoing issues with diagnosing diastolic dysfunction in this cohort, partly owing to the poor applicability of ...
David J. Clancy +5 more
doaj +1 more source
Teamwork in the intensive care unit. [PDF]
American Psychologist, 2018 Intensive care units (ICUs) provide care to the most severely ill hospitalized patients. Although ICUs increasingly rely on interprofessional teams to provide critical care, little about actual teamwork in this context is well understood. The ICU team is typically comprised of physicians or intensivists, clinical pharmacists, respiratory therapists ...
Jennifer N. Ervin +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
, 2014 Objective: To detect the effects of care bundle that is prepared depending on guidelines for central line associated infections. Material and Method: Patients in a tertiary medical intensive care unit were followed up during one year period in terms of ...
Fatma Ülger +7 more
core +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source