Results 41 to 50 of about 6,984,190 (307)
, 2014 Neuroleptic malignant syndrome (NMS) is a rare but life-threatening clinical manifestation induced by neuroleptic medication. Although NMS is regarded as a psychiatric diagnosis, its treatment requires a systematic approach and thus intensive care follow-
Yeşim Beckmann +4 more
core +1 more source
A comprehensive neuromonitoring approach in a large animal model of cardiac arrest
Animal Models and Experimental Medicine, 2022 Background Anoxic brain injuries represent the main determinant of poor outcome after cardiac arrest (CA). Large animal models have been described to investigate new treatments during CA and post‐resuscitation phase, but a detailed model that includes ...
Filippo Annoni +11 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Family care in intensive care units
Southern African Journal of Critical Care, 2019 No Abstract.
openaire +5 more sources
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Canadian Respiratory Journal, 2022 Dexmedetomidine (DEX), which is reported to be a newly discovered, novel α-2 adrenoceptor agonist, is known to exhibit anti-inflammatory properties in several diseases.
Xianfeng Chen +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
A Subtle Presentation of Pharyngitis and Pneumonia: Lemierre Syndrome
Case Reports in PulmonologyLemierre syndrome (LS) is a rare condition with an estimated incidence of 1–10/1,000,000 per year defined as a complication of an oral and nasopharyngeal infection with secondary septicemia leading to septic emboli and internal jugular vein thrombosis ...
Federico Bellini +10 more
doaj +1 more source
Long-term cognitive outcomes among unselected ventilated and non-ventilated ICU patients
Journal of Intensive Care, 2017 Background Cognitive dysfunction is an important long-term complication of critical illness associated with reduced quality of life, increase in healthcare costs, and institutionalization.
José Raimundo A. de Azevedo +8 more
doaj +1 more source
Annals of Intensive Care, 2020 Background No recommendation exists about the timing and setting for tracheal intubation and mechanical ventilation in septic shock. Patients and methods This prospective multicenter observational study was conducted in 30 ICUs in France and Spain.
C. Darreau +32 more
doaj +1 more source