Results 41 to 50 of about 576,929 (268)
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The Effectiveness of Bevacizumab in COVID-19 Pneumonia Among Critically Ill Patients
Egyptian Journal of Critical Care Medicine, 2022 Background Bevacizumab, an antiangiogenic drug, is being evaluated for the management of novel coronavirus disease (COVID-19) pneumonia among critically ill patients.
Karthikkeyan Rajachandran +6 more
doaj +1 more source
SARS in the intensive care unit [PDF]
Current Infectious Disease Reports, 2004 Approximately 20% of patients with severe acute respiratory syndrome (SARS) develop respiratory failure that requires admission to an intensive care unit (ICU). Old age, comorbidity, and elevated lactate dehydrogenase on hospital admission are associated with increased risk for ICU admission.
Joynt, Gavin M., Yap, H. Y.
openaire +2 more sources
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Long-term cognitive outcomes among unselected ventilated and non-ventilated ICU patients
Journal of Intensive Care, 2017 Background Cognitive dysfunction is an important long-term complication of critical illness associated with reduced quality of life, increase in healthcare costs, and institutionalization.
José Raimundo A. de Azevedo +8 more
doaj +1 more source
Canadian Respiratory Journal, 2022 Dexmedetomidine (DEX), which is reported to be a newly discovered, novel α-2 adrenoceptor agonist, is known to exhibit anti-inflammatory properties in several diseases.
Xianfeng Chen +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Subtle Presentation of Pharyngitis and Pneumonia: Lemierre Syndrome
Case Reports in PulmonologyLemierre syndrome (LS) is a rare condition with an estimated incidence of 1–10/1,000,000 per year defined as a complication of an oral and nasopharyngeal infection with secondary septicemia leading to septic emboli and internal jugular vein thrombosis ...
Federico Bellini +10 more
doaj +1 more source
Annals of Intensive Care, 2020 Background No recommendation exists about the timing and setting for tracheal intubation and mechanical ventilation in septic shock. Patients and methods This prospective multicenter observational study was conducted in 30 ICUs in France and Spain.
C. Darreau +32 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source