Results 121 to 130 of about 338,524 (295)

Association between NT‐proBNP changes and clinical outcomes in paediatric patients with heart failure: Insights from PANORAMA‐HF and PARADIGM‐HF

ESC Heart Failure, EarlyView.
This post hoc analysis of the PANORAMA‐HF paediatric heart failure trial evaluates the correlation of baseline and clinical changes in NT‐proBNP and clinical outcomes in children with heart failure due to left ventricular systolic dysfunction. This is the first prospective, randomized large‐scale study to demonstrate that changes in NT‐proBNP levels ...
Robert Shaddy, Jianjian Gong, Tania Garito, Susan Solar‐Yohay, Sijia Zhang, Margaret F. Prescott, Damien Bonnet, Paul F. Kantor, Michael Burch, Chad Mao, Antoinette Cilliers, Charles Canter, Yuk Law, Giorgia Grutter, Jou Kou Wang, Aamir Jeewa, Joseph Rossano, on behalf of PANORAMA‐HF investigators   +17 more
wiley   +1 more source

Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts

European Journal of Heart Failure, EarlyView.
Markers of progression to heart failure (HF). Gal‐4, galectin‐4; GDF‐15, growth differentiation factor 15; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; ST2, suppression of tumorigenicity‐2. ABSTRACT Aims Biomarkers associated with asymptomatic ventricular dysfunction might improve risk stratification and identify pathways leading to heart ...
Anna Dieden, Nicolas Girerd, Filip Ottosson, John Molvin, Manan Pareek, Olle Melander, Erasmus Bachus, Lennart Råstam, Ulf Lindblad, Bledar Daka, Margrét Leósdóttir, Peter M. Nilsson, Michael H. Olsen, Andrew L. Clark, John G.F. Cleland, Christian Delles, Arantxa González, Zohra Lamiral, Kevin Duarte, Patrick Rossignol, Faiez Zannad, Petri Gudmundsson, Amra Jujić, Martin Magnusson   +23 more
wiley   +1 more source

Practical management of repeated life‐threatening status epilepticus in Alternating Hemiplegia of Childhood: Case report and literature review

Epileptic Disorders, EarlyView.
Abstract Background Alternating Hemiplegia of Childhood (AHC) is a severe channelopathy that manifests before 18 months of age, primarily caused by pathogenic variants in the ATP1A3 gene. It is characterized by recurrent and disabling episodes of plegia, dystonia, dysautonomia, along with chronic neurological features and cardiac arrhythmias. About 50%
Ramona Cordani, Livia Pisciotta, Michela Stagnaro, Maria Margherita Mancardi, Elisabetta Lampugnani, Luca Manfredini, Lino Nobili, Edvige Veneselli, Elisa De Grandis   +8 more
wiley   +1 more source

Biallelic NEXN variants and fetal onset dilated cardiomyopathy: two independent case reports and revision of literature

Italian Journal of Pediatrics
Background Dilated cardiomyopathy (DCM) is an etiologically heterogeneous group of diseases of the myocardium. With the rapid evolution in laboratory investigations, genetic background is increasingly determined including many genes with variable ...
Irene Picciolli, Angelo Ratti, Berardo Rinaldi, Anwar Baban, Maria Iascone, Gaia Francescato, Alessia Cappelleri, Monia Magliozzi, Antonio Novelli, Giovanni Parlapiano, Anna Maria Colli, Nicola Persico, Stefano Carugo, Fabio Mosca, Maria Francesca Bedeschi   +14 more
doaj   +1 more source

Variation in Performance of Neonatal Intensive Care Units in the United States

JAMA pediatrics, 2017
J. Horbar, Erika M. Edwards, Lucy T. Greenberg, Kate A. Morrow, R. Soll, M. Buus-Frank, J. Buzas   +6 more
semanticscholar   +1 more source

ILAE neuroimaging task force highlight: MRI detection of early life epilepsy caused by focal cortical dysplasia

Epileptic Disorders, EarlyView.
Abstract The ILAE Neuroimaging Task Force aims to publish educational case reports that highlight basic aspects of neuroimaging in epilepsy consistent with the ILAE's educational mission. Here, we describe a case series of three neonates with focal cortical dysplasia (FCD)‐related drug‐resistant epilepsy who underwent surgical intervention. The purpose
Nathan T. Cohen, L. Gilbert Vezina, Chima Oluigbo, Tayyba Anwar, John Archer, Boris C. Bernhardt, Lorenzo Caciagli, Fernando Cendes, Yotin Chinvarun, Luis Concha, Paolo Federico, Eliane Kobayashi, Godwin Ogbole, Stefan Rampp, Anna Elisabetta Vaudano, Z. Irene Wang, Shuang Wang, Gavin P. Winston, William D. Gaillard   +18 more
wiley   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Time to death and its predictors among neonates admitted with sepsis in neonatal intensive care unit at comprehensive specialized hospitals in Northeast Ethiopia

Frontiers in Pediatrics
BackgroundIn impoverished nations like Ethiopia, neonatal sepsis contributes significantly to neonatal mortality. Despite variations in the specific timing of death and predictors of neonatal mortality associated with sepsis across different settings ...
Muluken Amare Wudu, Yemane Eshetu Bekalu, Endalk Birrie Wondifraw, Tarikua Afework Birhanu, Molla Kassa Hailu, Melaku Ashagire Belete, Yaregal Semanew Endeshaw   +6 more
doaj   +1 more source

Bactericidal, Virucidal, and Biocompatible Properties of 3D Printed Materials Enhanced with Copper and Zinc Nanoparticles

Global Challenges, EarlyView.
As population growth, urbanization, and climate change increase the spread of pathogens, hospital infections now affect 1 in 31 patients, costing billions annually. This study presents a new approach by integrating copper and zinc oxide nanoparticles into 3D‐printed materials.
Andrei‐Florin Sandu, Lauren Acton, Phillip Gould   +2 more
wiley   +1 more source

Prevalence and risk factors for postpartum depression and stress among mothers of preterm and low birthweight infants admitted to a neonatal intensive care unit in Accra, Ghana

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 131-137, April 2025.
Abstract To determine the prevalence of postpartum depression (PPD) and postpartum stress (PPS) and identify associated risk factors among mothers of preterm and low birth weight (LBW) infants. We conducted a secondary analysis of data collected from 255 mothers with preterm and LBW infants admitted to the neonatal intensive care unit (NICU) at Korle ...
John Pellegrino, Paddington T. Mundagowa, Kwame Sarfo Sakyi, Prince Gyebi Owusu, Babbel Agbinko‐Djobalar, Leila M. Larson, Mufaro Kanyangarara   +6 more
wiley   +1 more source