Results 51 to 60 of about 134,915 (306)

Determining optimal outcome measures in a trial investigating no routine gastric residual volume measurement in critically ill children [PDF]

open access: yes, 2020
Background Choosing trial outcome measures is important. When outcomes are not clinically relevant or important to parents/patients, trial evidence is less likely to be implemented into practice.
Andrzejewska, Izabela   +16 more
core   +2 more sources

Psychological Safety Among Interprofessional Pediatric Oncology Teams in Germany: A Nationwide Survey

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn   +4 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Parents’ and carers’ experiences of transition and aftercare following a child's discharge from a paediatric intensive care unit to an in-patient ward setting:A qualitative systematic review [PDF]

open access: yes, 2019
Objectives: To explore parents’ experiences of transition and aftercare following their child’s discharge from a pediatric intensive care unit to an inpatient ward.Methods: A qualitative systematic review was conducted.
Evans, Catrin   +2 more
core   +2 more sources

Hypertension in the Pediatric Intensive Care Unit [PDF]

open access: yesJournal of Pediatric Intensive Care, 2015
Hypertension in the pediatric intensive care unit (PICU) is common and it contributes to the overall morbidity and mortality. Patients may present with hypertensive emergencies or hypertension can manifest itself later in PICU course. Although hypertension can be seen in most patients during hospitalization, patients with some specific diseases and ...
Gokhan, Olgun, Eunice, John
openaire   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A deep learning model for real-time mortality prediction in critically ill children

open access: yesCritical Care, 2019
Background The rapid development in big data analytics and the data-rich environment of intensive care units together provide unprecedented opportunities for medical breakthroughs in the field of critical care.
Soo Yeon Kim   +11 more
doaj   +1 more source

Clinical significance of potential drug-drug interactions in a pediatric intensive care unit: A single-center retrospective study.

open access: yesPLoS ONE, 2021
Despite the high prevalence of potential drug-drug interactions in pediatric intensive care units, their clinical relevance and significance are unclear.
Yu Hyeon Choi   +7 more
doaj   +1 more source

Outcome of meningococcal septic shock in childhood [PDF]

open access: yes, 2008
Yearly approximately 5000 children (0-18 years) are admitted to specialized pediatric intensive care units (PICU) in the Netherlands. Among these children, although relatively low in number, patients with meningococcal sepsis or septic shock form a well ...
Buysse, C.M.P. (Corinne)
core   +1 more source

A Review of Best Practices for Monitoring and Improving Inpatient Pediatric Patient Experiences. [PDF]

open access: yes, 2020
ContextAchieving high-quality patient-centered care requires assessing patient and family experiences to identify opportunities for improvement. With the Child Hospital Consumer Assessment of Healthcare Providers and Systems Survey, hospitals can assess ...
Hays, Ron D   +3 more
core  

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