Results 81 to 90 of about 6,110,800 (292)

Optimal productive size of hospital’s intensive care units [PDF]

Hospital, Intensive Care Units, Returns to Scale, Optimal ...
James Moises, Vivian Valdmanis, Hervé Leleu   +2 more
core  

Real-World Effectiveness of Nirsevimab Against RSV-LRTI and Bronchiolitis Hospitalization: Results from the 2024–2025 Italian Universal Immunization Campaign in Newborns

Viruses
Respiratory syncytial virus (RSV) remains a leading cause of lower respiratory tract infection (LRTI) and hospitalization in early infancy. Following the introduction of universal nirsevimab prophylaxis in Italy during the 2024–2025 RSV season, we ...
Cinzia Auriti, Camilla Gizzi, Matteo Riccò, Roberto Bellù, Mario Giuffrè, Adele Fabiano, Caterina Cacace, Paola Cavicchioli, Armando Cuttano, Susanna Di Valerio, Cristiana Germini, Marcello Napolitano, Giulia Paviotti, Chiara Peila, Serafina Perrone, Simona Pesce, Gianfranco Scarpelli, Grazia Scutti, Giuseppina Spanedda, Alex Staffler, Massimo Agosti, on behalf of the Italian Working Group on RSV Prophylaxis of Italian Society of Neonatology   +21 more
doaj   +1 more source

Evaluation of Central Line Associated Blood Stream Infection (CLABSI) Prevention Bundle in Pediatric Intensive Care Unit, Zagazig University Hospitals [PDF]

Zagazig University Medical Journal
Background: Central line-associated bloodstream infection is a major healthcare-associated complication in pediatric and neonatal intensive care units, leading to increased morbidity and mortality. Although evidence-based prevention bundles reduce CLABSI
Mohamed Romih, Ahmed Hassan Atia, Dalia Abdulrahman   +2 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. [PDF]

, 2014
OBJECTIVE: Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate. The aim of this consensus is to provide support to the bedside clinician regarding the diagnosis, management and monitoring of shock.
Vitón-Castillo, Adrián Alejandro, Mebazaa, A, Mebazaa, A. (Alexandre), Antonelli, M, Rhodes, A. (Andrew), Backer, D. (Daniel) de, Pinsky, MR, Teboul, JL, Bakker, J. (Jan), Vincent, JL, Pinsky, Michaël, Christoph Hofer, Jean Louis Vincent, Teboul, J.L. (Jean Louis), Beale, R, Daniel De Backer, Jaeschke, R, Rhodes, A, Jaeschke, Roman, Hofer, C, Jaeschke, R. (Roman), Teboul, Jean Louis, Mebazaa, Alexandre, Cecconi, M. (Maurizio), De Backer, Daniel, Antonelli, Massimo, Massimo Antonelli, Antonelli, M. (Massimo), Viruez-Soto, José Antonio, Bakker, Jan, Hofer, C. (Christoph), Auza-Santivañez, Jhossmar Cristians, Maurizio Cecconi, Vincent, J.-L. (Jean-Louis), Jean Louis Teboul, Roman Jaeschke, Beale, R. (Richard), Vincent, Jean Louis, Hofer, Christoph, Pinsky, M.R. (Michael), Michael R. Pinsky, Bakker, J, Richard Beale, Rhodes, Andrew, Alexandre Mebazaa, Luperón Loforte, Daysi, Cecconi, M, De Backer, D, Jan Bakker, Beale, Richard, Bakker, Jan; id_orcid, Cecconi, Maurizio, Andrew Rhodes   +52 more
core   +2 more sources

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

A gap between need and reality: neonatal nursing staff requirements on a German intensive care unit

Pediatric Reports, 2014
Recently, new staffing rules for neonatal nurses in intensive care units (ICU) were issued in Germany, using categories of care of the British Association of Perinatal Medicine as blueprint.
Christian Patry, Monika Schindler, Julia Reinhard, Steffen Hien, Süha Demirakca, Thomas Böhler, Thomas Schaible   +6 more
doaj   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Interdisciplinary communication in the intensive care unit [PDF]

, 2007
BACKGROUND: Patient safety research has shown poor communication among intensive care unit (ICU) nurses and doctors to be a common causal factor underlying critical incidents in intensive care.
B.H. Cuthbertson, Mearns, Kathryn, Reader, Tom, Flin, Rhona, T.W. Reader, Cuthbertson, Brian H., K. Mearns, Reader, Tom W., Flin, R., Cuthbertson, Brian, R. Flin   +10 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source