Results 121 to 130 of about 1,631,497 (414)

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

Posture Recognition in the Critical Care Settings using Wearable Devices [PDF]

open access: yesarXiv, 2021
Low physical activity levels in the intensive care units (ICU) patients have been linked to adverse clinical outcomes. Therefore, there is a need for continuous and objective measurement of physical activity in the ICU to quantify the association between physical activity and patient outcomes.
arxiv  

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

Nutrition in Pediatric Intensive Care Units

open access: yesJournal of Pediatric Emergency and Intensive Care Medicine, 2023
The limited energy stores and fast metabolism of sick children in the intensive care unit, as well as the intense stress caused by the critical illness, reveal the importance of nutrition.
Hasan Ağın   +6 more
doaj   +1 more source

Investigating Why Clinicians Deviate from Standards of Care: Liberating Patients from Mechanical Ventilation in the ICU [PDF]

open access: yes
Clinical practice guidelines, care pathways, and protocols are designed to support evidence-based practices for clinicians; however, their adoption remains a challenge. We set out to investigate why clinicians deviate from the ``Wake Up and Breathe'' protocol, an evidence-based guideline for liberating patients from mechanical ventilation in the ...
arxiv   +1 more source

Data Resource Profile: the Dutch National Intensive Care Evaluation (NICE) Registry of Admissions to Adult Intensive Care Units.

open access: yesInternational Journal of Epidemiology, 2015
Data Resource Profile: the Dutch National Intensive Care Evaluation (NICE) Registry of Admissions to Adult Intensive Care Units Nick van de Klundert, Rebecca Holman,* Dave A. Dongelmans and Nicolette F. de Keizer National Intensive Care Evaluation (NICE)
Nick van de Klundert   +3 more
semanticscholar   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

open access: yesFEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu   +4 more
wiley   +1 more source

Seizures in Children with Influenza during the 2022–2023 Winter Season, a Case Series

open access: yesClinics and Practice
Influenza is a viral infection presenting with general symptoms such as fever, headache, fatigue, and involvement of airways or the gastrointestinal tract. The nervous system may be involved, but less frequently.
Francesca Peranzoni   +4 more
doaj   +1 more source

Noise Sources and Levels in Intensive Care Units

open access: yesTürk Yoğun Bakim Derneği Dergisi, 2015
Objective: Noise has been an important problem for both patients and healthcare workers at hospitals. The study was aimed at determining noise sources and noise levels intensive care units. Material and Method: Noise level measurements were performed in
Emine Kol, Emine İlaslan, Serpil İnce
doaj   +1 more source

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