Results 241 to 250 of about 1,415,466 (305)

Equal and safe use of flexible bronchoscopy in intensive care units. [PDF]

ERJ Open Res
Konge L, Annema J.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Consequences of a toxic workplace environment on psychological safety in anaesthesia and intensive care: A European survey. [PDF]

Eur J Anaesthesiol Intensive Care
Crisan I, Südy R, Gisselbaek M, Abramovich I, Hockenhull B, Borisova D, Karras G, Marty AP, Podesta AMC, Ringvold EM, Berger-Estilita J, Saxena S.   +11 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Metabolic acidosis and sodium bicarbonate therapy in critically ill patients: A multinational survey of international and Chinese practitioners. [PDF]

Crit Care Resusc
Caroli A, Zhou L, Chaba A, Eastwood G, Hikasa Y, Kitisin N, Li T, Li W, Lin X, Liu Y, Lv C, Maeda A, McNamara M, Nübel J, Pan C, Raykateeraroj N, Spano S, Xu X, Zhang H, Ke L, Serpa Neto A.   +20 more
europepmc   +1 more source

About time: Echocardiography update in UK intensive care curriculum. [PDF]

J Intensive Care Soc
Akhtar W.
europepmc   +1 more source

Evaluation and perspectives of the OrphanAnesthesia project - a survey among anesthesiologists in Germany. [PDF]

BMC Anesthesiol
Gaik C, Münster T, Kretz FJ, Gude P.
europepmc   +1 more source

Knowledge Assessment on the Management of Acute Cor Pulmonale: An Interdisciplinary Survey Study. [PDF]

J Clin Med
Bolt L, Rudiger A, Turk A, Arrigo M, Huber LC.   +4 more
europepmc   +1 more source

How generative AI is shaping research software development and maintenance at a research-intensive university. [PDF]

Open Res Eur
Besser SA, Jensen EA, Katz DS.
europepmc   +1 more source