Results 11 to 20 of about 187,220 (221)

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Fertility Desire and Intention of People Living with HIV/AIDS in Tanzania: A call for Restructuring Care and Treatment Services. [PDF]

, 2013
Scaling up of antiretroviral therapy (ART) is currently underway in sub-Saharan Africa including, Tanzania, increasing survival of people living with HIV/AIDS (PLWHA). Programmes pay little attention to PLWHA's reproductive health needs.
A Kline, A Sunderland, ALF Kaida, ALS Sarna, ALSC Moore, AN Dyer SJ, BLJ Nattabi, Deodatus C Kakoko, DHJ Cooper, EJHA Mmbaga, EJHA Mmbaga, Elia J Mmbaga, FJ LA Oliveira, Germana H Leyna, GR TE Wilson, GS Ogilvie, JLPKA Chen, LMC Myer, LRK Myer, Mangi J Ezekiel, MFL Nduna, NBS, NBS, OTDO Oladapo, RHWM Gray, SHL Sunderam, SJ Gange, SJMJ Kanniappan, SMDR Craft, UNAIDS, WFM Tamene, YB Hogg RS   +31 more
core   +3 more sources

A Workplace Study of Three Children’s Mental Health Centres in Southern Ontario [PDF]

, 2003
Rationale Recent cuts to resources for children and families requiring children’s mental health services coupled with an increase in the number of children needing these services have left staff in many agencies feeling extremely challenged in providing ...
Frensch, Karen, Harvey, C., Mandell, Deena, Stalker, Carol   +3 more
core   +1 more source

Interventions for improving employment outcomes for workers with HIV [PDF]

, 2015
Acknowledgements We would like to thank Cochrane Work Trials Search Co-ordinators Leena Isotalo and Kaisa Neuvonen for developing the search strategy and Managing Editor Jani Ruotsalainen and Co-ordinating Editor Jos Verbeek for editing the text and ...
Mngoma, Nomusa, Okpo, Emmanuel, Robinson, Rachel   +2 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Latvia's democratic resistance: a forgotten episode from the Second World War [PDF]

, 2009
In summer 1943 politicians representing the four main political parties of Latvia's democratic years came together to establish a movement which would both resist the German occupation and prevent the return of the Red Army. They considered the key to re-
Swain, G.
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

A reformation model of compliance to improve the property tax revenue generation in Malaysian local governments [PDF]

, 2016
This study is aimed at proposing an extension on Fisher’s model of compliance behavior based on empirical findings on property tax revenue generated in Malaysian local government.
Kasim, Rozilah
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source