Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Exploring Factors Influencing Pre-Service Teachers' Intention to Use GenAI for Instructional Design: A Grounded Theory Study. [PDF]
Behav Sci (Basel)Wu R, Wang X, Nie Y, Lv P, Luo X.
europepmc +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
How does bitterness perception correlate with the intention to use traditional Chinese medicine? An analysis of double-edged sword effects based on the stimuli-organism-response framework. [PDF]
Front Public HealthWang G, Hua M, Xie X, Zhang Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Factors associated with intention to use an educative mHealth application among high-risk target groups in health prevention. [PDF]
MhealthBickmann P, Froböse I, Grieben C.
europepmc +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
The development of pre-service biology teachers' intention to use digital incremental scaffolds: insights from guided online training. [PDF]
Front PsycholOffermann M +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Intention to use and perceived satisfaction with a digital tool for dementia prevention among the Dutch general public: a cross-sectional study. [PDF]
BMC Public Healthde Rijke TJ +8 more
europepmc +1 more source