Results 91 to 100 of about 1,536,123 (255)

Relational and conjunctive binding functions dissociate in short-term memory [PDF]

open access: yes, 2015
Remembering complex events requires binding features within unified objects (conjunctions) and holding associations between objects (relations). Recent studies suggest that the two functions dissociate in long-term memory (LTM). Less is known about their
Della Sala, Sergio   +7 more
core   +1 more source

The Sense of Agency in Autism Spectrum Disorders: a Dissociation between Prospective and Retrospective Mechanisms?

open access: yesFrontiers in Psychology, 2015
While a large number of studies have reported impairments in social and interpersonal abilities in individuals with autism spectrum disorder (ASD), relatively few studies have focused on self-related knowledge in this population.
Tiziana eZalla, Marco eSperduti
doaj   +1 more source

Sense of agency for future-directed intentions: Intentional binding for intermediate outcomes

open access: yes, 2019
Intentions can be present-directed or future-directed. Given that previous studies have primarily focused on understanding present-directed intentions, we studied sense of agency (SoA) for future-directed intentions by focusing on intermediate action-outcome events. The intermediate outcome exactly predicted the final perceptual outcome.
Saurabh Ranjan, Narayanan Srinivasan
openaire   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Mine is earlier than yours: Causal beliefs influence the perceived time of action effects

open access: yesFrontiers in Psychology, 2012
When a key press causes a stimulus, the key press is perceived later and the stimulus earlier than key presses and stimuli presented independently. This bias in time perception has been linked to the intention to produce the effect and thus been called ...
Carola eHaering, Andrea eKiesel
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Motor-sensory recalibration modulates perceived simultaneity of cross-modal events atdifferent distances

open access: yesFrontiers in Psychology, 2013
A popular model for the representation of time in the brain posits the existence of a single, central clock. In that framework, temporal distortions in perception are explained by contracting or expanding time over a given interval.
Brent D Parsons   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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