Results 101 to 110 of about 367,581 (336)
Free Will: Real or Illusion - A Debate [PDF]
Debate on free will with Christian List, Gregg Caruso, and Cory Clark.
Caruso, Gregg D. +2 more
core
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The Pertinence of Incontinence
In this paper I suggest a reconstruction of the traditional concepts of con-tinent and incontinent action. This reconstruction proceeds along the lines of a standpoint of bounded rationality.
António Zilhão
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
How people explain their own and others’ behavior: A theory of lay causal explanations
A theoretical model is proposed that speci¬fies lay causal theo¬ries of behavior; and supporting experimental evidence is presented. The model’s basic assumption is that diffe¬rent types of behavior trigger different hypotheses concerning the types of ...
Gisela eBöhm, Hans-Rüdiger ePfister
doaj +1 more source
Review of The Stuff of Thought by Steven Pinker (2008) (review revised 2019) [PDF]
I start with some famous comments by the philosopher (psychologist) Ludwig Wittgenstein because Pinker shares with most people (due to the default settings of our evolved innate psychology) certain prejudices about the functioning of the mind, and ...
Starks, Michael
core
Negation, expressivism, and intentionality [PDF]
Many think that expressivists have a special problem with negation. I disagree. For if there is a problem with negation, I argue, it is a problem shared by those who accept some plausible claims about the nature of intentionality.
Carballo, Alejandro Pérez
core
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
A BRIEF EVALUATION OF HIJĀʾ (SATIRE) DEVELOPMENT IN ANCIENT ARABIC POETRY
This study was aimed to show that the purpose of Hijāʾ (invective, lampoon, satire poetry) was directly linked to war. invective poetry of War is one of the main types or genres of Classical Arabic poetry, but the studies did not explain the reason for
Layla DARWISH
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

