Results 51 to 60 of about 176,077,545 (250)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Bioterrorism and Biological Warfare, from Past to the Present: A classic review

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2015
Bioterrorism is defined as any terrorist action of intentional release or dissemination of highly pathogenic biological agents, including a variety of microorganisms or biological toxins.
Majid Zare Bidaki, Mahdi Balalimood
doaj  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

An architecture for intentional agents [PDF]

open access: yes, 2013
The goal of this research is to investigate the use of Answer Set Prolog (ASP) based languages and action languages in the design and implementation of intelligent agents.
Blount, Justin
core   +2 more sources

Problems the influence of parasitological pollution on the disease of parasitosis in Ukraine and in Kharkiv region

open access: yesАктуальні проблеми сучасної медицини, 2019
Summary: The article is dedicated the problem of diagnosing parasites, including socially significant ones. The relevance of the problem of parasites is associated with their prevalence, polymorphism of clinical manifestations, which complicate the ...
Oksana, Krystyna
doaj  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Detecting Agency from the Biological Motion of Veridical vs Animated Agents [PDF]

open access: yes, 2007
The ability to detect agency is fundamental for understanding the social world. Underlying this capacity are neural circuits that respond to patterns of intentional biological motion in the superior temporal sulcus and temporoparietal junction.
Heatherton, Todd F   +7 more
core   +2 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Division of Select Agents & Toxins : protecting America from dangerous [PDF]

open access: yes
Responsible for regulating the possession, use, and transfer of select agents and the importation of infectious biological agents into the U.S. that could cause disease in humans.CS256096GPublication date from document properties.infographic_dsat.pdfCDC ...

core  

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