Results 41 to 50 of about 5,746,913 (265)
Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations
Advanced Science, EarlyView.Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford +3 more
wiley +1 more source
Relaciones InternacionalesConsiderando que se asiste a una crisis de la gobernanza sobre el escenario de seguridad internacional en el marco de la cual Argentina es un país relevante estratégicamente pero periférico y militarmente indefenso, este artículo examina el discurrir de
Emilse Calderón
doaj +1 more source
A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance
Advanced Science, EarlyView.Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng +12 more
wiley +1 more source
“Política exterior argentina e interés nacional: una mirada a Latinoamérica”
Diálogos, 2008 El objetivo del presente artículo es argumentar, en base al posicionamiento de Argentina frente a tres hechos históricos extremos ocurridos en Latinoamérica, la existencia de una política exterior propia, y a su vez demostrar que, al contrario de lo que ...
Melisa Deciancio, Fernanda López Franz
doaj +1 more source
Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States
Advanced Science, EarlyView.Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton +13 more
wiley +1 more source
LA VECINDAD CON ESTADOS UNIDOS: INTERÉS NACIONAL Y OPINIÓN PÚBLICA
Foro Internacional, 2015 Se analizan los determinantes individuales que afectan las percepciones costo-beneficio de la vecindad con Estados Unidos en la opinión pública mexicana. Se construye a su vez un modelo estadístico multivariado de regresión lineal.
Laura De Olden
doaj +1 more source
Revista de Interés Público (REDIP) | Año 1 | Número 1
, 2017 La Revista de Interés Público (REDIP) de la Secretaría de Extensión Universitaria de la Facultad de Ciencias Jurídicas y Sociales, nace como consecuencia de la observación del desarrollo creciente entre nuestras prácticas constitucionales, de una forma ...
Revista de Interés Público
core
Advanced Science, EarlyView.ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo +10 more
wiley +1 more source
Angewandte Chemie, EarlyView.Using NMR and molecular simulations, we map how RNA engages FUS LC‐RGG1 within condensates through electrostatic, π‐stacking, and polar contacts. These multivalent RNA contacts help stabilize RNA within FUS condensates while also reshaping condensate composition and dynamics.
Tongyin Zheng +6 more
wiley +2 more sources