Results 101 to 110 of about 247 (164)
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley +1 more source
Deterministic Fiber‐Optic Spectral Engineering Enables Three‐Color Multiplexed Two‐Photon Microscopy
A simulation‐guided spectral‐engineering framework maps the nonlinear parameter space of a fiber laser platform to identify balanced three‐band excitation states. The resulting 960, 1080, and 1175 nm femtosecond pulses deliver nJ‐level energies for low‐cross‐talk chromatically multiplexed two‐photon microscopy.
Marvin Edelmann +5 more
wiley +1 more source
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
ABSTRACT Attention‐deficit/hyperactivity disorder (ADHD) is increasingly linked to disturbances in circadian regulation, yet this temporal dimension remains insufficiently integrated into research and clinical practice. This perspective synthesises current evidence on circadian misalignment in ADHD, reframing commonly reported sleep disturbances and ...
Ping Wang, Bo Zeng, Bivek Singh
wiley +1 more source
Orthostatic Myoclonus—Clinical and Electrophysiological Features in a Large Retrospective Cohort
Abstract Background Orthostatic myoclonus is characterized by irregular, lower limb myoclonic bursts during stance and is a major cause of postural instability and falls. However, studies are limited, and little is known about its pathophysiology. Objectives We sought to define the clinical and electrophysiological features of orthostatic myoclonus in ...
Sai A. Nagaratnam +8 more
wiley +1 more source
The Application of Telemedicine in Surgery
This figure provides an overview of the content presented in this article. Telemedicine is integrated throughout the entire surgical workflow, with distinct applications across the preoperative, intraoperative, and postoperative phases. These applications are enabled by a suite of supporting technologies, while the associated implementation challenges ...
Yufan Yang +8 more
wiley +1 more source
Abstract Background Spastic paresis, resulting from central nervous system lesions, significantly impairs functional performance. In the framework of the International Classification of Functioning, Disability, and Health, functional performance was defined as functioning at the activity level in relation to the impairment of body functions and ...
Martina Hoskovcova +13 more
wiley +1 more source
Abstract Background Transcranial temporal interference stimulation (TIs) targeting the subthalamic nucleus (STN) is a novel noninvasive neuromodulation approach with potential to improve motor symptoms in Parkinson's disease (PD). However, its underlying neuroimaging mechanisms remain unclear.
Yongxin Xu +19 more
wiley +1 more source
ABSTRACT Purpose Increase clinical acceptance of MRE and DTI by shortening the scan time by half and providing diffusive and mechanical property maps that are inherently co‐registered. This proof‐of‐concept study evaluates the simultaneous DTI‐MRE acquisition in the human brain and compares its results to conventional DTI and MRE measurements.
Shujun Lin +4 more
wiley +1 more source

