Results 71 to 80 of about 49,326 (299)

Ejection of Stars with Relativistic Velocities

Open Astronomy, 2016
We present the results of numerical simulations performed in terms of modified Hills' scenario involving two supermassive black holes (SMBHs). In contrast to the classic Hills scenario (Hills 1988), here one component of the ordinary stellar binary ...
Dryomova G., Dryomov V., Tutukov A.
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Coffee Consumption Is Associated With Later Age‐at‐Onset of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Observation studies suggest that coffee consumption may lower the risk and delay the age‐at‐onset (AAO) of Parkinson's disease (PD). The aim of this study was to explore the causal relationship and genetic association between coffee consumption and the AAO, risk, and progression of PD. Using Mendelian randomization, we identified a significant
Dariia Kuzovenkova, Lang Liu, Ziv Gan‐Or, Konstantin Senkevich   +3 more
wiley   +1 more source

A Study of Nine Extremely Low Mass Ratio-contact Binary Systems

The Astronomical Journal
Low-mass ratio systems (LMR) are a very interesting class of contact eclipsing binaries challenging the theoretical models of stability. These systems are also considered possible progenitors of the rare low-mass optical transients called red novae.
Eleni Lalounta, Panagiota-Eleftheria Christopoulou, Athanasios Papageorgiou, C. E. Ferreira Lopes, Márcio Catelan   +4 more
doaj   +1 more source

The implications of close binary stars for star-disk interactions [PDF]

Proceedings of the International Astronomical Union, 2007
AbstractThe presence of close (≲ 0.1 AU) stellar companions must greatly alter the circumstellar environment of classical T Tauri stars, including severe truncation if not elimination of circumstellar disks. It is thus remarkable how little impact the presence of a close companion has on our observable diagnostics for accretion and outflow.
openaire   +2 more sources

Gravitational interactions of stars with supermassive black hole binaries – II. Hypervelocity stars [PDF]

Monthly Notices of the Royal Astronomical Society, 2018
Supermassive black holes (SMBHs) in galactic nuclei can eject hypervelocity stars (HVSs). Using restricted three-body integrations, we study the properties of stars ejected by circular, binary SMBHs as a function of their mass ratios $q = M_2 / M_1$ and separations $a$, focusing on the stellar velocity and angular distributions.
Daniel Kasen, Daniel Kasen, Siva Darbha, Eric R. Coughlin, Eric R. Coughlin, Eliot Quataert   +5 more
openaire   +3 more sources

Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Preserved resting‐state functional MRI (rs‐fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs‐fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice.
Jean Paul Medina Carrion, Mario Stanziano, Ludovico D'Incerti, Davide Sattin, Stefania Ferraro, Davide Rossi Sebastiano, Francesca Giulia Magnani, Alice Deruti, Davide Fedeli, Ludovico Minati, Francesca Epifani, Marina Grisoli, Matilde Leonardi, Maria Grazia Bruzzone, Anna Nigri, Cristina Rosazza   +15 more
wiley   +1 more source

The First Photometric Analysis of Two Low-mass-ratio Contact Binary Systems in TESS Survey

The Astronomical Journal
Low-mass-ratio ( q ) contact binary systems are progenitors of stellar mergers such as blue stragglers or fast-rotating FK Com stars. In this study, we present the first light curve analysis of two newly identified low mass-ratio contact binary systems ...
Qiyuan Cheng, Jianping Xiong, Xu Ding, Kaifan Ji, Jiao Li, Chao Liu, Jiangdan Li, Jingxiao Luo, Xin Lyu, Zhanwen Han, Xuefei Chen   +10 more
doaj   +1 more source

Gas Dynamic Simulation of the Star-Planet Interaction using a Binary Star Model [PDF]

Proceedings of the International Astronomical Union, 2011
AbstractWe have performed numerical simulations of the interaction between a “hot Jupiter” planet and gas of the stellar wind using a numerical code developed for investigations of binary stars. With this code, we have modeled the structure of the gaseous flow in the system HD 209458.
V. I. Shematovich, P. V. Kaygorodov, Dmitry Bisikalo, D. E. Ionov   +3 more
openaire   +3 more sources