Results 131 to 140 of about 22,628,091 (313)

Match_Motif: A rapid computational tool to assist in protein-protein interaction design. [PDF]

Protein Sci, 2022
Zacharias M.
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Applying self-determination theory to behavior change technologies: insights from two projects in the health domain

Frontiers in Psychology
In the health domain, patients often need to adopt and maintain behaviors that are tedious, unpleasant, or even painful, such as taking medication regularly, being more physically active, or maintaining a diet.
Rebecca Gerstenberg, Emil Rosenlund Høeg, Jolene Van der Kaap-Deeder, Marc Hassenzahl   +3 more
doaj   +1 more source

A scalable solid-state nanoporous network with atomic-level interaction design for carbon dioxide capture. [PDF]

Sci Adv, 2022
Mao H, Tang J, Day GS, Peng Y, Wang H, Xiao X, Yang Y, Jiang Y, Chen S, Halat DM, Lund A, Lv X, Zhang W, Yang C, Lin Z, Zhou HC, Pines A, Cui Y, Reimer JA.   +18 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Child-centered home service design for a family robot companion

Frontiers in Robotics and AI
The home robot-based child activity service aims to cultivate children’s social emotions. A design theme was produced by interviewing child development experts and parents. The activity service is composed of 50 plays and 70 conversations.
Hyo Jeong Lym, Hyo In Son, Da-Young Kim, Juhyun Kim, Min-Gyu Kim, Jae Hee Chung   +5 more
doaj   +1 more source

Toward basic interaction design [PDF]

, 2008
"Where are the artists?" asked Hiroshi Ishii, a professor at MIT Media Lab, adressing a panel at the 2008 conference on human factors in computing systems, this year entitled Art.Science.Balance. The question reflected the overall atmosphere of the event
Franinovic, Karmen
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A Novel User Emotional Interaction Design Model Using Long and Short-Term Memory Networks and Deep Learning. [PDF]

Front Psychol, 2021
Chen X, Huang R, Li X, Xiao L, Zhou M, Zhang L.   +5 more
europepmc   +1 more source