Results 81 to 90 of about 22,628,091 (313)

Pattern languages in HCI: A critical review [PDF]

, 2006
This article presents a critical review of patterns and pattern languages in human-computer interaction (HCI). In recent years, patterns and pattern languages have received considerable attention in HCI for their potential as a means for developing and ...
Anderson B., Anderson B., Andy Dearden, Barfield L., Bayle E., Beck K., Borchers J., Coad P., Fincher S., Garlan D., Janet Finlay, Kafura D., Saunders W. S.   +12 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Assessing urban heat island hotspots through virtual and physical boundary analysis with space syntax

Geocarto International
This study presents a three-dimensional framework for assessing the microclimate in urban canyons. The temperature data were collected using UAV-mounted sensors and calibrated against meteorological records.
Chia-Hsing Chen, Ko-Chiu Wu
doaj   +1 more source

Enhancing Creativity in Interaction Design: Alternative Design Brief [PDF]

, 2008
This paper offers a critique of the design brief as it is currently used in teaching interaction design and proposes an alternative way of developing it.
Dix, Alan, Sas, Corina
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Experiential disparities in social VR: uncovering power dynamics and inequality

Frontiers in Virtual Reality
Social Virtual Reality (SVR) offers new forms of social interaction, identity expression, and embodied experiences, but it has also revealed significant issues related to social inequalities and unequal power dynamics within virtual worlds.
Cayley MacArthur, Eugene Kukshinov, Daniel Harley, Trisha Pawar, Nirali Modi, Lennart E. Nacke   +5 more
doaj   +1 more source

Designing Interaction Design

, 2022
Interaction design is changing as a response to new social, technological, and environmental contexts, which bring new scopes of complexity into the frame interaction designers are con-cerned with. These changes demand that established ways of designing are in need of revision, because failing to do so will inevitably lead us to reinforce established ...
openaire   +1 more source

PickCells: A Physically Reconfigurable Cell-composed Touchscreen [PDF]

, 2019
Touchscreens are the predominant medium for interactions with digital services; however, their current fixed form factor narrows the scope for rich physical interactions by limiting interaction possibilities to a single, planar surface.
Coutrix, C., Goguey, A., Jones, M., Lucero, A., Neate, T., Nigay, L., Pearson, J., Ranjan Sahoo, D., Robinson, S., Roudaut, A., Steer, C., Subramanian, S., Tokuda, Y.   +12 more
core   +6 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Sense-making Strategies for the Interpretation of Visualizations—Bridging the Gap between Theory and Empirical Research

Multimodal Technologies and Interaction, 2017
Making sense of visualizations is often an open and explorative process. This process is still not very well understood. On the one hand, it is an open question which theoretical models are appropriate for the explanation of these activities.
Margit Pohl, Johanna Doppler Haider
doaj   +1 more source