Results 81 to 90 of about 5,392,711 (295)

The Effect of Musical Environments on Designers’ Attention: Persistent Music Listening Interferes with Attention

open access: yesBehavioral Sciences
Research indicates that music can influence human cognitive functions. Diverse musical settings can affect alertness, orientation, and executive control of attention in various populations.
Shulan Yu, Xinran Chen
doaj   +1 more source

Influencing interaction: Development of the design with intent method [PDF]

open access: yes, 2009
Persuasive Technology has the potential to influence user behavior for social benefit, e.g. to reduce environmental impact, but designers are lacking guidance choosing among design techniques for influencing interaction. The Design with Intent Method, a ‘
Harrison, DJ   +3 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Prototyping Spatial Interactions

open access: yesDigitCult@Scientific Journal on Digital Cultures, 2021
A growing field in the interaction design practice is the domain of connected and interactive spaces. The idea of ubiquitous computing, that was originated in the late 1980s and the beginning of the 1990s, is now seeking maturity, and technology ...
Pierluigi Dalla Rosa
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Holographic Mixed-Reality Interfaces for Enhanced BIM-Driven Facility Management: A Case Study [PDF]

open access: yesE3S Web of Conferences
Persistent operation and management (O&M) inefficiency stems from fragmented spatial knowledge. 2D paper-based drawings are piecemeal; desktop BIM lacks context; tethered VR causes motion sickness and drift.
Yang Tianlun   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Appliance design for pervasive computing [PDF]

open access: yes, 2003
The First International Conference on Appliance Design offered the opportunity for computer scientists, electronic engineers, designers, architects, and business strategists to discuss and to blend all the perspectives of design—physical, functional ...
Roussos, George
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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